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Abstract B020: SF3B1 hotspot mutations confer sensitivity to PARP inhibition through a defective replication stress response

Title: Abstract B020: SF3B1 hotspot mutations confer sensitivity to PARP inhibition through a defective replication stress response
Authors: Bland, P; Saville, H; Wai, PT; Curnow, L; Nieminuszczy, J; Ravindran, N; Barker, HE; Wright, J; Yu, L; Mavrommati, I; Peck, B; Gazinska, P; Pemberton, HN; Gulati, A; Guppy, N; Roxanis, I; Pratt, G; Oldreive, C; Stankovic, T; Barlow, S; Kalirai, H; Coupland, SE; Broderick, R; Alsafadi, S; Houy, A; Stern, M-H; Pettit, S; Choudhary, JS; Haider, S; Niedzwiedz, W; Lord, CJ; Natrajan, R
Publisher Information: American Association for Cancer Research (AACR)
Publication Year: 2023
Collection: Queen Mary University of London: Queen Mary Research Online (QMRO)
Subject Terms: Cancer; Genetics; Rare Diseases; Orphan Drug; Women's Health; 5.1 Pharmaceuticals; 2.1 Biological and endogenous factors
Document Type: article in journal/newspaper
File Description: b020 - b020
Language: unknown
Relation: Molecular Cancer Therapeutics; https://qmro.qmul.ac.uk/xmlui/handle/123456789/104114
DOI: 10.1158/1535-7163.targ-23-b020
Availability: https://qmro.qmul.ac.uk/xmlui/handle/123456789/104114; https://doi.org/10.1158/1535-7163.targ-23-b020
Accession Number: edsbas.E98D614C
Database: BASE