Minimally invasive and endoscopic versus open necrosectomy for necrotising pancreatitis: A pooled analysis of individual data for 1980 patients
| Title: | Minimally invasive and endoscopic versus open necrosectomy for necrotising pancreatitis: A pooled analysis of individual data for 1980 patients |
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| Authors: | Van Brunschot S; Hollemans RA; Bakker OJ; Besselink MG; Baron TH; Beger HG; Boermeester MA; Bollen TL; Bruno MJ; Carter R; French JJ; Coelho D; Dahl B; Dijkgraaf MG; Doctor N; Fagenholz PJ; Farkas G; Castillo CFD; Fockens P; Freeman ML; Gardner TB; Goor HV; Gooszen HG; Hannink G; Lochan R; McKay CJ; Neoptolemos JP; Olah A; Parks RW; Peev MP; Raraty M; Rau B; Rosch T; Rovers M; Seifert H; Siriwardena AK; Horvath KD; Van Santvoort HC |
| Source: | Gut, April 2018 |
| Publisher Information: | BMJ Publishing Group |
| Publication Year: | 2018 |
| Collection: | Newcastle University Library ePrints Service |
| Description: | © Article author(s). Objective Minimally invasive surgical necrosectomy and endoscopic necrosectomy, compared with open necrosectomy, might improve outcomes in necrotising pancreatitis, especially in critically ill patients. Evidence from large comparative studies is lacking. Design We combined original and newly collected data from 15 published and unpublished patient cohorts (51 hospitals; 8 countries) on pancreatic necrosectomy for necrotising pancreatitis. Death rates were compared in patients undergoing open necrosectomy versus minimally invasive surgical or endoscopic necrosectomy. To adjust for confounding and to study effect modification by clinical severity, we performed two types of analyses: logistic multivariable regression and propensity score matching with stratification according to predicted risk of death at baseline (low: |
| Document Type: | article in journal/newspaper |
| Language: | unknown |
| Relation: | https://eprints.ncl.ac.uk/247422 |
| Availability: | https://eprints.ncl.ac.uk/247422 |
| Accession Number: | edsbas.EA1CDB6E |
| Database: | BASE |