Percutaneous Ethanol Injection plus Radioiodine Versus Radioiodine Alone in the Treatment
| Title: | Percutaneous Ethanol Injection plus Radioiodine Versus Radioiodine Alone in the Treatment |
|---|---|
| Authors: | Of Large Toxic Thyroid Nodules; Matteo Zingrillo; Sergio Modoni; Md Matteo Conte; Md Vincenzo Frusciante; Vincenzo Trischitta Md |
| Contributors: | The Pennsylvania State University CiteSeerX Archives |
| Source: | http://jnm.snmjournals.org/content/44/2/207.full.pdf. |
| Collection: | CiteSeerX |
| Description: | Therapeutic options for toxic thyroid nodules (TTNs) are sur-gery, radioiodine (RAI), and percutaneous ethanol injection (PEI). Surgery is generally considered for TTNs larger than 4 cm. However, some patients may be at high surgical risk. The purpose of the study was to evaluate the efficacy of 2 non-surgical modalities for these TTNs. Methods: Twenty-two patients with TTNs larger than 4 cm were randomly assigned to 2 different treatments: to 11 (subgroup A), RAI was admin-istered at a dose of 12,580 kBq/mL of nodular volume (NV) and was corrected for 100 % 24-h 131I uptake (RAIU); to 11 (subgroup B), 2 – 4 PEI sessions (ethanol injected 30 % NV) preceded 2 mo of 24-h RAIU and RAI dosing. Inclusion criteria were clinical and biochemical hyperthyroidism; a sin-gle palpable, hot nodule at 99mTc scintigraphy; and high sur-gical risk or refusal to have surgery. Patients gave informed |
| Document Type: | text |
| File Description: | application/pdf |
| Language: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.564.8320; http://jnm.snmjournals.org/content/44/2/207.full.pdf |
| Availability: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.564.8320; http://jnm.snmjournals.org/content/44/2/207.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| Accession Number: | edsbas.EA21659A |
| Database: | BASE |