| Title: |
Cardiovascular Risk Factors Associated With the Metabolically Healthy Obese (MHO) Phenotype Compared to the Metabolically Unhealthy Obese (MUO) Phenotype in Children |
| Authors: |
Genovesi S.; Antolini L.; Orlando A.; Gilardini L.; Bertoli S.; Giussani M.; Invitti C.; Nava E.; Battaglino M. G.; Leone A.; Valsecchi M. G.; Parati G. |
| Contributors: |
Genovesi, S; Antolini, L; Orlando, A; Gilardini, L; Bertoli, S; Giussani, M; Invitti, C; Nava, E; Battaglino, M; Leone, A; Valsecchi, M; Parati, G |
| Publisher Information: |
Frontiers Media S.A. |
| Publication Year: |
2020 |
| Collection: |
Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| Subject Terms: |
children; HOMA index; metabolically healthy obesity; Uric Acid; waist-height ratio |
| Description: |
Background: In pediatric age the prevalence of obesity is high. Obese children who do not have other risk factors than excess weight have been defined as “metabolically healthy obese” (MHO). Aim: The aim of this study is to evaluate, in a population of obese children, the prevalence of the MHO and “metabolically unhealthy obese” (MUO) phenotype. Furthermore, we evaluated the distribution of Uric Acid, HOMA index and Waist-Height ratio (W-Hr) in the MHO and MUO sub-groups and the impact of these non-traditional risk factors on the probability to be MUO. Methods: In 1201 obese children and adolescents [54% males, age (±SD) 11.9 (±3.0) years] weight, height, waist circumference, systolic (SBP) and diastolic (DBP) blood pressure, pubertal status, glucose, insulin, HDL cholesterol, triglycerides and Uric Acid serum values were assessed. MUO phenotype was defined as the presence of at least one of the following risk factors: SBP or DBP ≥ 90th percentile, glycaemia ≥ 100 mg/dl, HDL cholesterol |
| Document Type: |
article in journal/newspaper |
| File Description: |
ELETTRONICO |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/32117055; info:eu-repo/semantics/altIdentifier/wos/WOS:000517203500001; volume:11; journal:FRONTIERS IN ENDOCRINOLOGY; https://hdl.handle.net/10281/265187 |
| DOI: |
10.3389/fendo.2020.00027 |
| Availability: |
https://hdl.handle.net/10281/265187; https://doi.org/10.3389/fendo.2020.00027 |
| Rights: |
info:eu-repo/semantics/openAccess ; license:Creative Commons ; license uri:http://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.EAF343FA |
| Database: |
BASE |