| Title: |
Classification of positive margins after resection of soft-tissue sarcoma of the limb predicts the risk of local recurrence |
| Authors: |
Gerrand CH; Wunder JS; Kandel RA; OSullivan B; Catton CN; Bell RS; Griffin AM; Davis AM |
| Source: |
Journal of Bone and Joint Surgery - British Volume, November 2001 |
| Publication Year: |
2001 |
| Collection: |
Newcastle University Library ePrints Service |
| Description: |
We considered whether a positive margin occurring after resection of a soft-tissue sarcoma of a limb would affect the incidence of local recurrence. Patients with low-grade liposarcomas were expected to be a low-risk group as were those who had positive margins planned before surgery to preserve critical structures. Two groups, however, were expected to be at a higher risk, namely, patients who had undergone unplanned excision elsewhere with a positive margin on re-excision and those with unplanned positive margins occurring during primary resection. Of 566 patients in a prospective database, 87 with positive margins after limb-sparing surgery and adjuvant radiotherapy were grouped according to the clinical scenario by an observer blinded to the outcome. The rate of local recurrence differed significantly between the two low- (4.2% and 3.6%) and the two high-risk groups (31.6% and 37.5%). This classification therefore provides useful information about the incidence of local recurrence after positive-margin resection. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
https://eprints.ncl.ac.uk/27737 |
| Availability: |
https://eprints.ncl.ac.uk/27737 |
| Accession Number: |
edsbas.EB68EA36 |
| Database: |
BASE |