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Use of Immunochromatographic SARS-CoV-2 Antigen Testing in Eight Long-Term Care Facilities for the Elderly

Title: Use of Immunochromatographic SARS-CoV-2 Antigen Testing in Eight Long-Term Care Facilities for the Elderly
Authors: Martina Ifko; Miha Skvarc
Source: Healthcare ; Volume 9 ; Issue 7 ; Pages: 868
Publisher Information: Multidisciplinary Digital Publishing Institute
Publication Year: 2021
Collection: MDPI Open Access Publishing
Subject Terms: immunochromatographic SARS-CoV-2 antigen test; clinical validation; POCT—point of care testing; long-term care
Description: The clinical validation of the NADAL COVID-19 antigen test (Nal von Minden, Moers, Germany) started in eight Slovenian long-term health care facilities in October 2020. The purpose of clinical validation is to implement the test into the everyday working process in long-term care (LTC) facilities and demonstrate how it can be used to mitigate the spread of the virus in these environments. The facilities compared the results of antigen tests to the results obtained using Cobas 6800 SARS-CoV-2 real-time reverse transcription polymerase chain reaction (RT-PCR) (Roche, USA). Sensitivity (86.96%, 95% CI: 66.41–97.23%) and specificity (88.24%, 95% CI: 80.35–93.77%) of the NADAL COVID-19 antigen test were good. Rapid antigen testing served well for early detection of infection and helped to prevent and control spread of the SARS Cov2 in six out of eight LTCs. Moreover, mini-outbreaks were quickly resolved in all six LTCs. Locally validated immunochromatographic SARS-CoV-2 antigen testing can be used to contain the spread of the virus in LTCs. Antigen tests also deliver accurate information very quickly if used early with a low threshold. The NADAL COVID-19 antigen test proved to be a good screening tool to detect SARS-COV-2 in LTCs.
Document Type: text
File Description: application/pdf
Language: English
Relation: Healthcare in Epidemics and Pandemics; https://dx.doi.org/10.3390/healthcare9070868
DOI: 10.3390/healthcare9070868
Availability: https://doi.org/10.3390/healthcare9070868
Rights: https://creativecommons.org/licenses/by/4.0/
Accession Number: edsbas.EB6A832B
Database: BASE