| Title: |
Mechanisms affecting the gut of preterm infants in enteral feeding trials: A nested cohort within a randomised controlled trial of lactoferrin |
| Authors: |
Young, Gregory R.; Berrington, Janet E.; Cummings, Stephen; Ewer, Andrew K.; Frau, Alessandra; Lett, Lauren; Probert, Christopher; Juszczak, Edmund; Kirby, John; Beck, Lauren C.; Renwick, Victoria L.; Lamb, Christopher A.; Lanyon, Clare; McGuire, William; Stewart, Christopher J.; Embleton, Nicholas D.; Dorling, Jon |
| Publisher Information: |
BMJ Publishing Group |
| Publication Year: |
2022 |
| Collection: |
University of Nottingham: Repository@Nottingham |
| Description: |
Objective: To determine the impact of supplemental bovine lactoferrin on the gut microbiome and metabolome of preterm infants.Design: Cohort study nested within a randomised controlled trial (RCT). Infants across different trial arms were matched on several clinical variables. Bacteria and metabolite compositions of longitudinal stool and urine samples were analysed to investigate the impact of lactoferrin supplementation.Setting: Thirteen UK hospitals participating in a RCT of lactoferrin.Patients: 479 infants born |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://nottingham-repository.worktribe.com/output/13173609; Archives of Disease in Childhood. Fetal and Neonatal Edition; Volume 108; Issue 3; Pagination 272-279 |
| DOI: |
10.1136/archdischild-2022-324477 |
| Availability: |
https://doi.org/10.1136/archdischild-2022-324477; https://nottingham-repository.worktribe.com/file/13173609/1/%20Mechanisms%20affecting%20the%20gut%20of%20preterm%20infants%20in%20enteral%20feeding%20trials%3A%20a%20nested%20cohort%20within%20a%20randomised%20controlled%20trial%20of%20lactoferrin; https://nottingham-repository.worktribe.com/output/13173609 |
| Rights: |
openAccess ; https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.EC1B0C07 |
| Database: |
BASE |