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Laser treatment monitoring with reflectance confocal microscopy

Title: Laser treatment monitoring with reflectance confocal microscopy
Authors: Guida S.; Longo C.; Amato S.; Rossi A. M.; Manfredini M.; Ciardo S.; Spadafora M.; Nistico S. P.; Mercuri S. R.; Rongioletti F.; Zerbinati N.; Pellacani G.
Contributors: Guida, S.; Longo, C.; Amato, S.; Rossi, A. M.; Manfredini, M.; Ciardo, S.; Spadafora, M.; Nistico, S. P.; Mercuri, S. R.; Rongioletti, F.; Zerbinati, N.; Pellacani, G.
Publisher Information: MDPI; Basel, Switzerland
Publication Year: 2023
Collection: Sapienza Università di Roma: CINECA IRIS
Subject Terms: laser; laser monitoring; pigmentation; reflectance confocal microscopy; rejuvenation; scar
Description: Laser treatments have become popular in Dermatology. In parallel to technologic development enabling the availability of different laser wavelengths, non-invasive skin imaging techniques, such as reflectance confocal microscopy (RCM), have been used to explore morphologic and qualitative skin characteristics. Specifically, RCM can be applied to cosmetically sensitive skin areas such as the face, without the need for skin biopsies. For these reasons, apart from its current use in skin cancer diagnosis, our systematic review reveals how RCM can be employed in the field of laser treatment monitoring, being particularly suitable for the evaluation of variations in epidermis and dermis, and pigmentary and vascular characteristics of the skin. This systematic review article aims to provide an overview on current applications of RCM laser treatment monitoring, while describing RCM features identified for different applications. Studies on human subjects treated with laser treatments, monitored with RCM, were included in the current systematic review. Five groups of treatments were identified and described: skin rejuvenation, scar tissue, pigmentary disorders, vascular disorders and other. Interestingly, RCM can assist treatments with lasers targeting all chromophores in the skin and exploiting laser induced optical breakdown. Treatment monitoring encompasses assessment at baseline and examination of changes after treatment, therefore revealing details in morphologic alterations underlying different skin conditions and mechanisms of actions of laser therapy, as well as objectify results after treatment.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/37374244; info:eu-repo/semantics/altIdentifier/wos/WOS:001015436900001; volume:59; issue:6; numberofpages:20; journal:MEDICINA; https://hdl.handle.net/11573/1687439
DOI: 10.3390/medicina59061039
Availability: https://hdl.handle.net/11573/1687439; https://doi.org/10.3390/medicina59061039
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.EC8A10FE
Database: BASE