| Title: |
Orchestrating a heist: uptake and storage of metals by apicomplexan parasites |
| Authors: |
Sloan, Megan A.; Aghabi, Dana; Harding, Clare R. |
| Publisher Information: |
Microbiology Society |
| Publication Year: |
2021 |
| Collection: |
University of Glasgow: Enlighten - Publications |
| Description: |
The acquisition and storage of metals has been a preoccupation of life for millennia. Transition metals, in particular iron, copper and zinc, have vital roles within cells. However, metals also make dangerous cargos; inappropriate uptake or storage of transition metals leads to cell death. This paradox has led to cells developing elegant and frequently redundant mechanisms for fine-tuning local metal concentrations. In the context of infection, pathogens must overcome further hurdles, as hosts act to weaponize metal availability to prevent pathogen colonization and spread. Here, we detail the methods used by the Apicomplexa, a large family of eukaryotic parasites, to obtain and store essential metals. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://eprints.gla.ac.uk/258219/1/258219.pdf; Sloan, Megan A. ORCID logoorcid:0000-0001-7659-4069 , Aghabi, Dana and Harding, Clare R. ORCID logoorcid:0000-0002-8428-0374 (2021) Orchestrating a heist: uptake and storage of metals by apicomplexan parasites. Microbiology , 167(12), 001114. (doi:10.1099/mic.0.001114 ) (PMID:34898419) (PMCID:PMC7612242) |
| DOI: |
10.1099/mic.0.001114 |
| Availability: |
https://eprints.gla.ac.uk/258219/; https://eprints.gla.ac.uk/258219/1/258219.pdf; https://doi.org/10.1099/mic.0.001114 |
| Rights: |
cc_by_4 |
| Accession Number: |
edsbas.ECE3C0C5 |
| Database: |
BASE |