| Title: |
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents |
| Authors: |
Cai, Song; Moutal, Aubin; Yu, Jie; Chew, Lindsey A.; Isensee, Jörg; Chawla, Reena; Gomez, Kimberly; Luo, Shizhen; Zhou, Yuan; Chefdeville, Aude; Madura, Cynthia; Perez-Miller, Samantha; Bellampalli, Shreya Sai; Dorame, Angie; Scott, David D.; François-Moutal, Liberty; Shan, Zhiming; Woodward, Taylor; Gokhale, Vijay; Hohmann, Andrea G.; Vanderah, Todd W.; Patek, Marcel; Khanna, May; Hucho, Tim; Khanna, Rajesh |
| Source: |
Science Translational Medicine ; volume 13, issue 619 ; ISSN 1946-6234 1946-6242 |
| Publisher Information: |
American Association for the Advancement of Science (AAAS) |
| Publication Year: |
2021 |
| Description: |
Protein-protein interaction inhibitor of the sodium NaV1.7 channel has analgesic effects in preclinical models of pain. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1126/scitranslmed.abh1314 |
| Availability: |
https://doi.org/10.1126/scitranslmed.abh1314; https://www.science.org/doi/pdf/10.1126/scitranslmed.abh1314 |
| Accession Number: |
edsbas.ED398D16 |
| Database: |
BASE |