| Title: |
Effects of isometric resistance training on resting blood pressure: individual participant data meta-analysis |
| Authors: |
Smart, Neil A; School of Science and Technology; orcid:0000-0002-8290-6409; Way, Damien; Carlson, Debra; Millar, Philip; McGowan, Cheri; Swaine, Ian; Baross, Anthony; Howden, Reuben; Ritti-Dias, Raphael; Wiles, Jim; Cornelissen, Veronique; Gordon, Ben; Taylor, Rod; Bleile, Bea; orcid:0000-0003-2254-6832 |
| Publisher Information: |
Lippincott Williams & Wilkins |
| Publication Year: |
2019 |
| Collection: |
University of New England at Armidale, New South Wales, Australia: e-publications@UNE |
| Subject Terms: |
Cardiology (incl. Cardiovascular Diseases) |
| Description: |
Background: Previous meta-analyses based on aggregate group-level data report antihypertensive effects of isometric resistance training (IRT). However, individual participant data meta-analyses provide more robust effect size estimates and permit examination of demographic and clinical variables on IRT effectiveness.Methods: We conducted a systematic search and individual participant data (IPD) analysis, using both a one-step and two-step approach, of controlled trials investigating at least 3 weeks of IRT on resting systolic, diastolic and mean arterial blood pressure.Results: Anonymized individual participant data were provided from 12 studies (14 intervention group comparisons) involving 326 participants (52.7% medicated for hypertension); 191 assigned to IRT and 135 controls, 25.2% of participants had diagnosed coronary artery disease. IRT intensity varied (8–30% MVC) and training duration ranged from 3 to 12 weeks. The IPD (one-step) meta-analysis showed a significant treatment effect for the exercise group participants experiencing a reduction in resting SBP of −6.22 mmHg (95% CI −7.75 to −4.68; P P = 0.002); and mean arterial blood pressure (MAP) of −4.12 mmHg (95% CI −5.39 to −2.85; P P P = 0.0004) and MAP MD −4.63 mmHg (95% CI −6.18 to −3.09: P Conclusion: This individual patient analysis confirms a clinically meaningful and statistically significant effect of IRT on resting SBP, DBP and mean arterial blood pressure. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://hdl.handle.net/1959.11/29497; une:1959.11/29497 |
| Availability: |
https://hdl.handle.net/1959.11/29497; https://rune.une.edu.au/web/retrieve/4e3cc790-54b5-4343-a760-bc6295b02768 |
| Rights: |
UNE Green ; http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Accession Number: |
edsbas.EDB4C51B |
| Database: |
BASE |