Effect of some inhibitors on neuraminidase of Newcastle disease virus Kudu 113 strain
| Title: | Effect of some inhibitors on neuraminidase of Newcastle disease virus Kudu 113 strain |
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| Authors: | Sunday Blessing Oladele; Paul Abdu; Andrew Jonathan Nok; King Akpofure; Nelson Esievo; Nicodemus Maashin Useh |
| Contributors: | The Pennsylvania State University CiteSeerX Archives |
| Source: | http://www.vef.unizg.hr/vetarhiv/papers/72-4/oladele.pdf. |
| Collection: | CiteSeerX |
| Description: | A total of two hundred samples from dialysed neuraminidase of Newcastle disease virus (NDV) Kudu 113 strain were used for the experiment. Fifty samples each were used for various concentrations of paranitrophenyl oxamic acid (PNPO), salicyl oxamic acid (SOA), silver nitrate (AgNO 3) and ethylene diamine tetra acetic acid (EDTA), to test their inhibition effects on the neuraminidase activity of NDV Kudu 113 strain in vitro, using thiobarbituric acid assay method. Of these inhibitors, AgNO 3 had the highest inhibition effect on the neuraminidase activity of NDV Kudu 113 strain. Silver nitrate reduced the activity of this enzyme from 140.24 µMol/min for enzyme without AgNO 3 to 32.36 µMol/min when AgNO 3 |
| Document Type: | text |
| File Description: | application/pdf |
| Language: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.431.257 |
| Availability: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.431.257; http://www.vef.unizg.hr/vetarhiv/papers/72-4/oladele.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| Accession Number: | edsbas.EEB5103A |
| Database: | BASE |