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Glioma mimicking a cystic infectious disease : A case report of multifocal, multicentric cystic glioblastoma

Title: Glioma mimicking a cystic infectious disease : A case report of multifocal, multicentric cystic glioblastoma
Authors: Kiss-Bodolay, Daniel; Weiner, Marc; Egervari, Kristof Levente; Eperon, Gilles Alain; Vargas Gomez, Maria Isabel; Migliorini, Denis; Lobrinus, Johannes Alexander; Harbarth, Stéphan Juergen; Bijlenga, Philippe Alexandre Pierre
Source: ISSN: 2152-7806 ; Surgical neurology international, vol. 16 (2025) 248.
Publication Year: 2025
Collection: Université de Genève: Archive ouverte UNIGE
Subject Terms: info:eu-repo/classification/ddc/613; info:eu-repo/classification/ddc/616.07; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/617; Cystic brain lesion; Cystic glioblastoma; Multicentric glioblastoma; Multifocal glioblastoma
Description: Background: Glioblastoma multiforme (GBM) is a highly aggressive malignant tumor known to be a great mimicker. Multicystic metastasis and cystic GBM are not rare but multicystic diffuse GBM was never reported before. Case description: We describe here the clinical course, the radiological characteristics, and the management of a patient with a diffuse cystic brain lesion. Even though the comprehensive bacterial, fungal, and parasitic work-up came back negative twice, the radiological and biological findings of the case presented in this work mislead an experienced multidisciplinary team. In a somewhat unexpected way, the pathological results showed a high-grade glial tumor. Conclusion: The case reported herein is an important reminder of the highly multimorph characteristics of GBM and the challenging differential diagnosis of cystic brain lesions.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/40656497; unige:186861
Availability: https://archive-ouverte.unige.ch/unige:186861
Rights: info:eu-repo/semantics/openAccess
Accession Number: edsbas.F075F72C
Database: BASE