| Title: |
Synthesis of Tetrahydroquinoline‐Embedded Bridged Benzothiaoxazepine‐1,1‐dioxides |
| Authors: |
Borgohain, Hemi; Devi, Runjun; Dheer, Divya; Borah, Biraj Jyoti; Shankar, Ravi; Das, Sajal Kumar |
| Contributors: |
DEPARTMENT OF Science and Technology, New Delhi, India |
| Source: |
European Journal of Organic Chemistry ; volume 2017, issue 45, page 6671-6679 ; ISSN 1434-193X 1099-0690 |
| Publisher Information: |
Wiley |
| Publication Year: |
2017 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
A diastereoselective synthesis of previously unknown tetrahydroquinoline‐containing bridged benzothiaoxazepine‐1,1‐dioxides is presented. The three‐step protocol uses readily available N ‐aryl‐2‐fluorobenzenesulfonamides and trans ‐2,3‐epoxy‐cinnamyl‐alcohol‐derived tosylates as the starting materials, involves N ‐alkylation of sulfonamides, intramolecular epoxide ring‐opening, and S N Ar reactions as the reaction steps, and requires only one chromatographic purification to access the desired products in good overall yields. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1002/ejoc.201701152 |
| Availability: |
https://doi.org/10.1002/ejoc.201701152; https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fejoc.201701152; https://onlinelibrary.wiley.com/doi/full/10.1002/ejoc.201701152 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.F10EDE10 |
| Database: |
BASE |