| Title: |
Sculpting with stiffness: rigidity as a regulator of morphogenesis |
| Authors: |
Shellard, Adam; Mayor, Roberto |
| Source: |
Biochemical Society Transactions (2023) (In press). |
| Publisher Information: |
Portland Press Ltd. |
| Publication Year: |
2023 |
| Collection: |
University College London: UCL Discovery |
| Subject Terms: |
development; mechanics; morphogenesis; rigidity; robustness; stiffness |
| Description: |
From a physical perspective, morphogenesis of tissues results from interplay between their material properties and the mechanical forces exerted on them. The importance of mechanical forces in influencing cell behaviour is widely recognised, whereas the importance of tissue material properties in vivo, like stiffness, has only begun to receive attention in recent years. In this mini-review, we highlight key themes and concepts that have emerged related to how tissue stiffness, a fundamental material property, guides various morphogenetic processes in living organisms. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10169511/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10169511/1/bst-2022-0826c.pdf; https://discovery.ucl.ac.uk/id/eprint/10169511/ |
| Rights: |
open |
| Accession Number: |
edsbas.F1E1D18 |
| Database: |
BASE |