Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio and Cardiorenal Syndrome Type 2 in the Systemic Sclerosis EUSTAR Cohort
| Title: | Tricuspid Annular Plane Systolic Excursion/Systolic Pulmonary Artery Pressure Ratio and Cardiorenal Syndrome Type 2 in the Systemic Sclerosis EUSTAR Cohort |
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| Authors: | Colalillo A.; Pellicano C.; Ananyeva L. P.; Hachulla E.; Cuomo G.; Gyorfi A. -H.; Czirjak L.; de Vries-Bouwstra J.; Mouthon L.; Poormoghim H.; Del Galdo F.; Hunzelmann N.; Spierings J.; Kuwana M.; Rosato E.; Gigante A.; Alunni Fegatelli D.; Garzanova L.; Launay D.; Di Vico C.; Bergmann C.; Varju C.; Scherer H. U.; Chaigne B.; Andalib E.; Alcacer-Pitarch B.; Moinzadeh P.; Van Laar J.; Watanabe S.; Distler O.; Jordan S.; Riemekasten G.; Marschner G.; Carreira P. E.; Martin M.; Siegert E.; Kedor C.; Simeon-Aznar C. -P.; Del Castillo A. G.; Marcoccia A.; Gabrielli A.; Landron C.; Smith V.; Airo P.; Lazzaroni M. -G.; Villiger P.; Adler S.; Iannone F.; Idolazzi L.; Muller-Ladner U.; Alegre-Sancho J. J.; Truchetet M. -E.; Dagna L.; Matucci Cerinic M.; Gheorghiu A. M.; Ramazan A. -M.; Cauli A.; Castellvi I.; Iudici M.; Solanki K.; Soukup T.; Allanore Y.; Limonta M.; Parvu M.; Moroncini G.; Zanatta E.; Selvi E.; Tanaka Y.; Selmi C. F.; Bielecka O. K.; Cutolo M.; Rednic S.; Henes J.; Kahl S.; Del Papa N.; Denton C.; Schmeiser T.; Brzosko M.; Sfikakis P.; Walker U.; Negrini S.; Riccieri V.; Fathi N.; Radic M.; Heitmann S.; Cantatore F. P.; de Souza Muller C.; Foti R.; Couto M.; Rezus E.; Balbir-Gurman A.; Krasowska D.; Opris-Belinski D.; Aringer M.; Anic B.; Baresic M.; Mayer M.; Yavuz S.; Agachi S.; Oksel F.; Zdrojewski Z.; Rodriguez-Pinto I.; Geroldinger-Simic M.; Lledo-Ibanez G. M.; Kubacki T.; Batalov A. |
| Contributors: | Colalillo, A.; Pellicano, C.; Ananyeva, L. P.; Hachulla, E.; Cuomo, G.; Gyorfi, A. -H.; Czirjak, L.; de Vries-Bouwstra, J.; Mouthon, L.; Poormoghim, H.; Del Galdo, F.; Hunzelmann, N.; Spierings, J.; Kuwana, M.; Rosato, E.; Gigante, A.; Alunni Fegatelli, D.; Garzanova, L.; Launay, D.; Di Vico, C.; Bergmann, C.; Varju, C.; Scherer, H. U.; Chaigne, B.; Andalib, E.; Alcacer-Pitarch, B.; Moinzadeh, P.; Van Laar, J.; Watanabe, S.; Distler, O.; Jordan, S.; Riemekasten, G.; Marschner, G.; Carreira, P. E.; Martin, M.; Siegert, E.; Kedor, C.; Simeon-Aznar, C. -P.; Del Castillo, A. G.; Marcoccia, A.; Gabrielli, A.; Landron, C.; Smith, V.; Airo, P.; Lazzaroni, M. -G.; Villiger, P.; Adler, S.; Iannone, F.; Idolazzi, L.; Muller-Ladner, U.; Alegre-Sancho, J. J.; Truchetet, M. -E.; Dagna, L.; Matucci Cerinic, M.; Gheorghiu, A. M.; Ramazan, A. -M.; Cauli, A.; Castellvi, I.; Iudici, M.; Solanki, K.; Soukup, T.; Allanore, Y.; Limonta, M.; Parvu, M.; Moroncini, G.; Zanatta, E.; Selvi, E.; Tanaka, Y.; Selmi, C. F.; Bielecka, O. K.; Cutolo, M.; Rednic, S.; Henes, J.; Kahl, S.; Del Papa, N.; Denton, C.; Schmeiser, T.; Brzosko, M.; Sfikakis, P.; Walker, U.; Negrini, S.; Riccieri, V.; Fathi, N.; Radic, M.; Heitmann, S.; Cantatore, F. P.; De Souza Muller, C.; Foti, R.; Couto, M.; Rezus, E.; Balbir-Gurman, A.; Krasowska, D.; Opris-Belinski, D.; Aringer, M.; Anic, B.; Baresic, M.; Mayer, M.; Yavuz, S.; Agachi, S. |
| Publication Year: | 2025 |
| Collection: | Università degli Studi di Cagliari: UNICA IRIS |
| Description: | Objective: The aim of the study was to evaluate the association between the tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (sPAP) ratio and estimated glomerular filtration rate (eGFR) and their association with mortality in the European Scleroderma Trials and Research (EUSTAR) cohort. Methods: Patients with systemic sclerosis (SSc) from the EUSTAR database with TAPSE, sPAP, and parameters required to calculate eGFR were included. Logistic regression and Cox regression analysis were performed to evaluate TAPSE/sPAP as a risk factor for chronic kidney disease (CKD) and overall survival. Results: A total of 2,370 patients with SSc were included; 284 (12%) patients had CKD stage 3a–5. TAPSE/sPAP (odds ratio [OR] 0.479; 95% CI 0.310–0.743; P < 0.001), arterial hypertension (OR 3.118; 95% CI 2.173–4.475; P < 0.001), diastolic dysfunction (OR 1.670; 95% CI 1.148–2.428; P < 0.01), and N-terminal pro-B-type natriuretic peptide (OR 1.165; 95% CI 1.041–1.304; P < 0.01) were associated with CKD stage 3a–5. TAPSE/sPAP ≤0.32 mm/mm Hg (hazard ratio [HR] 3.589; 95% CI 2.236–5.761; P < 0.001), eGFR |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/37458105; info:eu-repo/semantics/altIdentifier/wos/WOS:001074603400001; volume:77; issue:2; firstpage:257; lastpage:265; numberofpages:9; journal:ARTHRITIS CARE & RESEARCH; https://hdl.handle.net/11584/460965 |
| DOI: | 10.1002/acr.25196 |
| Availability: | https://hdl.handle.net/11584/460965; https://doi.org/10.1002/acr.25196; https://acrjournals.onlinelibrary.wiley.com/doi/10.1002/acr.25196 |
| Rights: | info:eu-repo/semantics/openAccess |
| Accession Number: | edsbas.F1FB2096 |
| Database: | BASE |