| Title: |
Purulent pericarditis in a patient with Turner`s syndrome |
| Authors: |
Hristov, Dimitar; Valeva, Velina; Cholakova, Ivona; Marinova, Zhenya; Mircheva, Lilyana |
| Source: |
Scripta Scientifica Vox Studentium; Vol 2 (2018): Suppl.1. Abstracts of the Sixth Black Sea Symposium for Young Scientists in Biomedicine (BSYSB), April 12-15 2018, Varna; 77 ; 2535-048X ; 2535-0471 |
| Publisher Information: |
Medical University of Varna |
| Publication Year: |
2018 |
| Collection: |
Varna Medical University Press: Journals |
| Subject Terms: |
pericarditis; Turner; inflammation; microbiology; effusions |
| Description: |
Introduction: Turner`s syndrome(TS), also known as 45,X is a genetic disorder where a female is partly or completely missing one of the X chromosomes. TS is characterized with low levels of estrogen and increased risk of a lot of disorders, with cardiac conditions being one of the most serious. Researches show that TS might be related to decreased levels of circulating T and B lymphocytes and reduced levels of serum immunoglobulin G and immunoglobulin M, in this way making the patients more susceptible to infections. The aim of this case report is to underline the acute inflammatory process caused by Staphylococcus aureus that developed as a comorbidity to a rare genetic condition.Materials and methods: We present a case of a 23-year-old woman with complaints of acute chest pain, drowsiness, fever up to 38 degrees oC and an episode of collapse without loss of consciousness. Blood tests showed high levels of leucocytes, erythrocyte sedimentation rate and C-reactive protein which confirmed the presence of an infection. A massive pericardial effusion was detected during echocardiography. It was drained and the microbiological analysis revealed Staphylococcus aureus as a major cause. During electrocardiography diffuse repolarisation abnormalities were found. A few consecutive chest X-rays revealed growing pleural effusions which were confirmed by the following computed tomography scan and positron emission tomography/computed tomography. In addition the pericardium turned out to be diffusely thickened with the presence of atelectasis and splenomegaly.Results: The treatment included drainage of the effusions, corticosteroids and a combination of antibiotics (Clindamycin, Levofloxacin, Ciprofloxacin, Metronidazole) aiming to eradicate the bacteria and alleviate the symptoms.Conclusion: In this era of antibiotic treatment, purulent pericarditis caused by S. aureus is an extremely rare condition. Its development on the background of TS makes it unique and interesting. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.14748/ssvs.v2i0.4607 |
| Availability: |
https://journals.mu-varna.bg/index.php/ssvs/article/view/4607; https://doi.org/10.14748/ssvs.v2i0.4607 |
| Rights: |
Всички публикации наScripta Scientifica Vox Studentium са лицензирани под Creative Commons Attribution 3.0 License. ; All work by Scripta Scientifica Vox Studentium is licensed under a Creative Commons Attribution 3.0 License. |
| Accession Number: |
edsbas.F2020B8F |
| Database: |
BASE |