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Valproic Acid: Special Considerations and Targeted Monitoring

Title: Valproic Acid: Special Considerations and Targeted Monitoring
Authors: Collins-Yoder, Angela; Lowell, Jordan
Source: Journal of Neuroscience Nursing ; volume 49, issue 1, page 56-61 ; ISSN 1945-2810 0888-0395
Publisher Information: Ovid Technologies (Wolters Kluwer Health)
Publication Year: 2017
Description: Valproic acid (VPA) is a medication used to treat multiple neuroscience conditions. It is an inexpensive and useful medication, with a low incidence of adverse drug events. Nonetheless, optimal clinical outcomes require that a series of screening and laboratory steps be followed before the initiation of VPA therapy. An additional aspect of pharmacovigilance is to recognize clinical patterns signaling genetic traits that preclude VPA, background of the black box warnings, targeted assessments, and laboratory monitoring indicated while on VPA. The intention of this article is to provide a focused summary of published information clinically relevant to prescribing and monitoring these patients.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1097/jnn.0000000000000259
Availability: https://doi.org/10.1097/jnn.0000000000000259; https://journals.lww.com/01376517-201702000-00014
Accession Number: edsbas.F2334E18
Database: BASE