| Title: |
Comparison of Heavy Metal and Disinfectant Resistance of S. aureus and Enterococcus Isolates with Antibiotic Resistance Profiles |
| Authors: |
Acar, Bahar Onaran; Şenarısoy, Hakan; Keyvan, Erhan |
| Source: |
OBM Genetics ; volume 09, issue 01, page 1-12 ; ISSN 2577-5790 |
| Publisher Information: |
LIDSEN Publishing Inc |
| Publication Year: |
2025 |
| Description: |
Antimicrobial resistance is one of the most significant threats to our present and future. Recently, it has been suggested that antibiotic-resistant microorganisms also exhibit resistance to heavy metals and disinfectants, and these resistance profiles may interact with each other. Microorganisms can be exposed to heavy metals and disinfectants in different ways in various environments. They are especially likely to be exposed to quaternary ammonium compounds used in the food industry or heavy metals due to tap water. Thus, microorganisms can adapt to their environment and gain resistance thanks to horizontal gene transfer. In our research, the heavy metal and disinfectant resistance profiles of 42 isolates whose antibiotic resistance profiles were determined in previous studies revealed the connection between the antibiotic - heavy metal - disinfectant resistances of the isolates. The resistance of the isolates to various heavy metals and disinfectants was determined by determining the minimum inhibition concentrations (MIC) using the broth microdilution method. MIC values obtained from the isolates were compared with those of the control well, and the resistance profiles of the isolates were determined. The isolates used in our research were found to be highly resistant to cobalt (83%), nickel (86%), and triclosan (81%). It has been observed that they are utterly resistant to zinc and lead. Based on the data obtained from the study, it is thought that the high rate of disinfectant and heavy metal resistance may be related to antibiotic resistance. However, more comprehensive studies are needed to understand this relationship fully. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| DOI: |
10.21926/obm.genet.2501278 |
| Availability: |
https://doi.org/10.21926/obm.genet.2501278; https://www.lidsen.com/journals/genetics/genetics-09-01-278/obm.genet.2501278.xml; https://www.lidsen.com/journals/genetics/genetics-09-01-278 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.F25C46C7 |
| Database: |
BASE |