| Title: |
Metabolic effects of dialyzate glucose in chronic hemodialysis: results from a prospective, randomized crossover trial |
| Authors: |
Raimann, Jochen G.; Kruse, Anja; Thijssen, Stephan; Kuntsevich, Viktoriya; Dabel, Pascal; Bachar, Mostafa; Diaz-Buxo, Jose A.; Levin, Nathan W.; Kotanko, Peter |
| Publisher Information: |
Oxford University Press |
| Publication Year: |
2012 |
| Collection: |
HighWire Press (Stanford University) |
| Subject Terms: |
Extracorporeal Treatments of Kidney Failure |
| Description: |
Background. There is no agreement concerning dialyzate glucose concentration in hemodialysis (HD) and 100 and 200 mg/dL (G100 and G200) are frequently used. G200 may result in diffusive glucose flux into the patient, with consequent hyperglycemia and hyperinsulinism, and electrolyte alterations, in particular potassium (K) and phosphorus (P). This trial compared metabolic effects of G100 versus G200. Methods. Chronic HD patients participated in this randomized, single masked, controlled crossover trial ( www.clinicaltrials.gov : #NCT00618033) consisting of two consecutive 3-week segments with G100 and G200, respectively. Intradialytic serum glucose (SG) and insulin concentrations (SI) were measured at 0, 30, 60, 120, 180, 240 min and immediately post-HD; P and K were measured at 0, 120, 180 min and post-HD. Hypoglycemia was defined as an SG |
| Document Type: |
text |
| File Description: |
text/html |
| Language: |
English |
| Relation: |
http://ndt.oxfordjournals.org/cgi/content/short/27/4/1559; http://dx.doi.org/10.1093/ndt/gfr520 |
| DOI: |
10.1093/ndt/gfr520 |
| Availability: |
http://ndt.oxfordjournals.org/cgi/content/short/27/4/1559; https://doi.org/10.1093/ndt/gfr520 |
| Rights: |
Copyright (C) 2012, European Renal Association - European Dialysis and Transplant Association |
| Accession Number: |
edsbas.F29C82E4 |
| Database: |
BASE |