| Title: |
Effort-based decision-making in ultra-high-risk for psychosis and bipolar disorder |
| Authors: |
Bora, E.; Cesim, E.; Eyuboglu, M. S.; Demir, M.; Yalincetin, B.; Ermis, C.; Uzman, Ozbek S.; Sut, E.; Demirlek, C.; Verim, B.; Baykara, B.; Inal, N.; Akdede, B. B. |
| Source: |
PSYCHOLOGICAL MEDICINE 54(11) 9 |
| Publication Year: |
2024 |
| Description: |
Background Effort-based decision-making has been proposed as a potential mechanism contributing to transdiagnostic motivational deficits in psychotic disorder and bipolar disorder. However, very limited information is available about deficits in effort-cost-decision-making in the early stages of psychotic disorder and no study has investigated effort allocation deficits before the onset of bipolar disorder. Our aim was to investigate effort-based-decision-making in ultra-high-risk for psychosis (UHR-P) and bipolar disorder (UHR-BD).Methods Effort-cost decision-making performance was evaluated in UHR-P (n = 72) and UHR-BD (n = 68) and healthy controls (n = 38). Effort-Expenditure for Reward Task (EEfRT) was used.Results Compared to controls, both UHR-P and UHR-BD groups were associated with a reduced possibility to choose the harder task when the reward magnitudes and/or the likelihood of receiving the reward were high. In both groups, effort allocation abnormalities were associated with poor social functioning.Conclusions The current findings suggest that difficulties in effort-cost computation are transdiagnostic markers of illness liability in psychotic and bipolar disorders. In early intervention services, effort-based decision-making abnormalities should be considered as a target for interventions to manage motivational deficits in individuals at high risk for psychosis and BD. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
https://aperta.ulakbim.gov.tr/record/276959; oai:aperta.ulakbim.gov.tr:276959 |
| Availability: |
https://aperta.ulakbim.gov.tr/record/276959 |
| Rights: |
info:eu-repo/semantics/openAccess ; http://www.opendefinition.org/licenses/cc-by |
| Accession Number: |
edsbas.F3CFD7F |
| Database: |
BASE |