| Title: |
Hygrophila auriculata seed extract mitigates infertility caused by streptozotocin-induced diabetes in Wistar albino rat model: Hygrophilla auriculata & infertility in Wistar albino rat |
| Authors: |
Myilraj, Gokilavani; Radhakrishnan, Arunkumar |
| Source: |
Letters In Animal Biology; Vol. 6 No. 1 (2026); 33-40 ; 2584-0479 |
| Publisher Information: |
Dr. Nasir Akbar Mir |
| Publication Year: |
2026 |
| Subject Terms: |
Male infertility; Diabetes; Hygrophila auriculata; Antioxidant; Lipid peroxidation; DNA fragmentation |
| Description: |
The present study investigates the effect of an ethanolic extract of Hygrophila auriculata seeds on the male reproductive organ weights, testicular lipid peroxidation and antioxidant potential, testosterone levels, and effects on sperm quality parameters in a streptozotocin (STZ)-induced diabetic male rat model, a widely used experimental model of diabetes-associated infertility. The extract was administered orally to STZ-induced diabetic rats to evaluate its effect on reproductive parameters in terms of evaluating sperm count, motility, viability, morphology and chromatin dispersal assay along with organ weight of male reproductive organs and serum testosterone levels. Antioxidant activity in testicular extract was assessed by measuring lipid peroxidation, glutathione peroxidase, superoxide dismutase, reduced glutathione and catalase assays. The results revealed that athough the male reproductive organ weights decreased significantly in diabetic and treatment groups as compared to the control, the semen quality parameters such as sperm count, motility and viability improved significantly (p |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://liabjournal.com/index.php/liab/article/view/299/92; https://liabjournal.com/index.php/liab/article/view/299 |
| DOI: |
10.62310/liab.v6i1.299 |
| Availability: |
https://liabjournal.com/index.php/liab/article/view/299; https://doi.org/10.62310/liab.v6i1.299 |
| Rights: |
Copyright (c) 2026 Gokila vani, Dr Arunkumar ; https://creativecommons.org/licenses/by/4.0 |
| Accession Number: |
edsbas.F4E9B43 |
| Database: |
BASE |