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Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives

Title: Relationship Between Epilepsy and Dreaming: Current Knowledge, Hypotheses, and Perspectives
Authors: de la Chapelle, Aurélien; Frauscher, Birgit; Valomon, Amandine; Ruby, Perrine, Marie; Peter-Derex, Laure
Contributors: Équipe Perception, Attention, Mémoire - Perception, Attention, Memory Team (CRNL-PAM); Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL); Université Claude Bernard Lyon 1 (UCBL); Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM); Université Jean Monnet (EPSCPE) (UJM EPE)-Université Jean Monnet (EPSCPE) (UJM EPE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL); Université Jean Monnet (EPSCPE) (UJM EPE)-Université Jean Monnet (EPSCPE) (UJM EPE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS); Montreal Neurological Institute and Hospital; McGill University = Université McGill Montréal, Canada
Source: ISSN: 1662-4548.
Publisher Information: CCSD; Frontiers
Publication Year: 2021
Collection: Inserm: HAL (Institut national de la santé et de la recherche médicale)
Subject Terms: dream; sleep; seizures; memory; epilepsy; emotion; sleep inertia; functional connectivity; dreaming; dream recall; default mode network; awakening; EEG–fMRI; MESH: Brain; MESH: Dreams; MESH: Electroencephalography; MESH: Humans; MESH: Mental Recall; MESH: Sleep; [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]
Description: International audience ; The interactions between epilepsy and sleep are numerous and the impact of epilepsy on cognition is well documented. Epilepsy is therefore likely to influence dreaming as one sleep-related cognitive activity. The frequency of dream recall is indeed decreased in patients with epilepsy, especially in those with primary generalized seizures. The content of dreams is also disturbed in epilepsy patients, being more negative and with more familiar settings. While several confounding factors (anti-seizure medications, depression and anxiety disorders, cognitive impairment) may partly account for these changes, some observations suggest an effect of seizures themselves on dreams. Indeed, the incorporation of seizure symptoms in dream content has been described, concomitant or not with a focal epileptic discharge during sleep, suggesting that epilepsy might directly or indirectly interfere with dreaming. These observations, together with current knowledge on dream neurophysiology and the links between epilepsy and sleep, suggest that epilepsy may impact not only wake- but also sleep-related cognition.
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/34552464; PUBMED: 34552464; PUBMEDCENTRAL: PMC8451887
DOI: 10.3389/fnins.2021.717078
Availability: https://hal.science/hal-04097580; https://hal.science/hal-04097580v1/document; https://hal.science/hal-04097580v1/file/delaChapelle_FN21.pdf; https://doi.org/10.3389/fnins.2021.717078
Rights: https://about.hal.science/hal-authorisation-v1/ ; info:eu-repo/semantics/OpenAccess
Accession Number: edsbas.F563D39E
Database: BASE