| Title: |
Comparison of outcomes between TAVI and SAVR in patients with bicuspid aortic valve stenosis |
| Authors: |
Faierstein, K; Moshkovitz, D M; Caller, T C; Ash, A A; Raphael, R R; Cohen, I C; Makmal, N M; Mazor Dray, E M; Maor, E M; Regev, E R; Segev, A S; Barbash, I B; Fefer, P F |
| Source: |
European Heart Journal ; volume 46, issue Supplement_1 ; ISSN 0195-668X 1522-9645 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2025 |
| Description: |
Background Aortic valve stenosis may be treated surgically or percutaneously using transcatheter aortic valve implantation (TAVI). Objectives This study aimed to compare outcomes of patients with bicuspid valve aortic stenosis undergoing TAVI versus surgical aortic valve replacement (SAVR). Methods A retrospective cohort analysis of 581 patients with bicuspid aortic valve stenosis was conducted, of whom 71 (12%) underwent TAVI and 510 (88%) underwent SAVR. The mean age was 76±8 and 60±12 in the TAVI and SAVR groups, respectively. We excluded patients with pure aortic insufficiency. Due to age differences, we employed a matched model and subsequently conducted a multivariate Cox regression analysis with adjustment for mortality predictors and baseline characteristics. Using this model, we investigated the association between the procedure conducted and overall survival, as well as post-procedural clinical outcomes. Results Overall, 125 patients died during a mean follow-up period of 9±4 years. Of these, 24 were in the TAVI group and 101 were in the SAVR group. The study demonstrated that patients with bicuspid aortic valve stenosis undergoing TAVI are more likely to die compared with SAVR [HR=6.4, 95% CI 3.9-10.4, p |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/eurheartj/ehaf784.2394 |
| Availability: |
https://doi.org/10.1093/eurheartj/ehaf784.2394; https://academic.oup.com/eurheartj/article-pdf/46/Supplement_1/ehaf784.2394/65217036/ehaf784.2394.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.F56B403C |
| Database: |
BASE |