| Title: |
No Association Between Breast Pain and Breast Cancer. A Prospective Cohort Study of 10,830 Symptomatic Women Presenting to a Breast Cancer Diagnostic Clinic |
| Authors: |
Dave, Rajiv V; Bromley, Hannah; Taxiarchi, Paraskevi; Camacho, Liz; Chatterjee, Sumohan; Barnes, Nicola; Hutchison, Gillian; Bishop, Paul; Hamilton, William; Kirwan, Cliona; Gandhi, Ashu |
| Source: |
Dave, R V, Bromley, H, Taxiarchi, P, Camacho, L, Chatterjee, S, Barnes, N, Hutchison, G, Bishop, P, Hamilton, W, Kirwan, C & Gandhi, A 2021, 'No Association Between Breast Pain and Breast Cancer. A Prospective Cohort Study of 10,830 Symptomatic Women Presenting to a Breast Cancer Diagnostic Clinic', British Journal of General Practice. |
| Publication Year: |
2021 |
| Collection: |
The University of Manchester: Research Explorer - Publications |
| Description: |
Background Women with breast pain constitute upto 20% of breast clinic attendees. Aim To investigate breast cancer incidence in women presenting with breast pain and establish health economics of referring women with breast pain to secondary care. Design & Setting Prospective cohort study of all consecutive women referred to a breast diagnostic clinic over 12 months. Methods Women were categorised by presentation into 4 distinct clinical groups and cancer incidence investigated. Results Of 10 830 women, 1972 (18%) were referred with breast pain, 6708 (62%) with lumps, 480 (4%) with nipple symptoms,1670 (15%) with ‘other’ symptoms. Mammography, performed in 1112 women with breast pain, identified cancer in 8 (0.7%). In 1972 women with breast pain, breast cancer incidence was 0.4% compared with ~5% in each of the three other clinical groups. Using ‘breast lump’ as reference, odds ratio (OR) of women referred with breast pain having breast cancer was 0.05 (95% confidence interval 0.02–0.09; P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| ISSN: |
0960-1643; 1478-5242 |
| Relation: |
info:eu-repo/semantics/altIdentifier/pissn/0960-1643; info:eu-repo/semantics/altIdentifier/eissn/1478-5242 |
| Availability: |
https://research.manchester.ac.uk/en/publications/17e46dc5-d842-4e3b-8fcc-28d90a651d72 |
| Rights: |
info:eu-repo/semantics/embargoedAccess |
| Accession Number: |
edsbas.F6C3237 |
| Database: |
BASE |