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Primary versus systemic-sclerosis-associated Raynaud's phenomenon: relationship with clinical and environmental factors

Title: Primary versus systemic-sclerosis-associated Raynaud's phenomenon: relationship with clinical and environmental factors
Authors: E. Favoino; M. Prete; V. Liakouli; A. Sisto; A. Corrado; P. Leone; G. Lisco; M. Vomero; E. Biancalana; E. Chiara; G. Emmi; V. Racanelli; A. Marcoccia; R. D. Grembiale; F. P. Cantatore; L. Navarini; P. Ruscitti; F. Ciccia; R. Giacomelli6; F. Perosa
Contributors: Favoino, E.; Prete, M.; Liakouli, V.; Sisto, A.; Corrado, A.; Leone, P.; Lisco, G.; Vomero, M.; Biancalana, E.; Chiara, E.; Emmi, G.; Racanelli, V.; Marcoccia, A.; Grembiale, R. D.; Cantatore, F. P.; Navarini, L.; Ruscitti, P.; Ciccia, F.; Giacomelli6, R.; Perosa, F.
Publication Year: 2025
Collection: Università degli Studi di Bari Aldo Moro: CINECA IRIS
Subject Terms: Systemic Sclerosis; secondary Raynaud's phenomenon; primary Raynaud's phenomenon; environmental factors; autoimmune hypothyroidism
Description: Objectives: Raynaud's phenomenon (RP) can be induced by stress and environmental factors, occurring as a primary disease (pRP) or associated with connective tissue disease. RP is seen in more than 95% of patients with systemic sclerosis (SSc) and may precede its diagnosis by several years. Accordingly, there is a clear need to identify those patients with RP who will eventually develop connective tissue disease, including SSc. The aim of this case-control study was to assess the association of SSc-RP versus pRP with respect to environmental factors, lifestyle habits, and clinical setting. Methods: A questionnaire was used to collect current data from 180 patients with SSc-RP and 103 with pRP. Statistical analyses were performed to identify possible risk factors for SSc-RP. Results: SSc-RP was found to be inversely associated with living in urban area (OR=0.37; p
Document Type: article in journal/newspaper
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/40183325; info:eu-repo/semantics/altIdentifier/wos/WOS:001578024200002; volume:43; issue:8; firstpage:1380; lastpage:1385; numberofpages:6; journal:CLINICAL AND EXPERIMENTAL RHEUMATOLOGY; https://hdl.handle.net/11586/535860; https://www.clinexprheumatol.org/abstract.asp?a=21465
DOI: 10.55563/clinexprheumatol/m7qpn3
Availability: https://hdl.handle.net/11586/535860; https://doi.org/10.55563/clinexprheumatol/m7qpn3; https://www.clinexprheumatol.org/abstract.asp?a=21465
Rights: info:eu-repo/semantics/openAccess ; license:Non specificato ; license uri:na
Accession Number: edsbas.F6D8782D
Database: BASE