| Title: |
P-566 Is the seminal oxidative stress the mirror of psychological stress perceived by infertile men? |
| Authors: |
Kooli, R; Bousabbeh, M; Sallem, A; Chebil, D; Haouas, Z; Mehdi, M |
| Source: |
Human Reproduction ; volume 38, issue Supplement_1 ; ISSN 0268-1161 1460-2350 |
| Publisher Information: |
Oxford University Press (OUP) |
| Publication Year: |
2023 |
| Description: |
Study question To assess the association between anxiety and depression scores and the levels of oxidative stress in seminal plasma of Tunisian infertile men. Summary answer Depression in hypofertile men is associated to higher levels of catalase in seminal plasma and thus to oxidative stress. What is known already Within the last decades, the knowledge concerning the link between psychological and oxidative stress in infertile men has been surging. In a limited number of studies aiming to elucidate the psychological aspect of male infertility, data related to increased incidence of depression and anxiety have been reported. It has also been reported that anxiety and depression may trigger the production of reactive free oxygen radicals leading to disruption of the balance between free radicals and antioxidants semen properties. Study design, size, duration This was a cross-sectional study performed in the Laboratory of Cytogenetics and Reproductive Biology of Fattouma Bourguiba University Teaching Hospital (Monastir Tunisia). A total of 282 patients were assessed for levels of anxiety and depression and evaluated for semen parameters. Among these, 105 patients were assessed for levels of superoxide dismutase (SOD) and 51 patients were evaluated for the levels of catalase in seminal plasma from September 2022 to January 2023. Participants/materials, setting, methods Were included patients addressed for semen quality assessment. All patients with a previously diagnosed psychological disorder, those who presented severe depression and/or anxiety symptoms or had a stressful life event were not included. Informed consent was obtained from all the participants. The subjects were evaluated for anxiety and depression symptoms using the valid Arab version of the HAD (Hospital Anxiety and Depression) scale. Semen analysis and results interpretation were performed according to 2021 WHO guidelines. Main results and the role of chance The mean HAD-D (depression) and HAD-A (anxiety) scores were of 6.56 ± 3.07 (IIQ ... |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1093/humrep/dead093.900 |
| Availability: |
https://doi.org/10.1093/humrep/dead093.900; https://academic.oup.com/humrep/article-pdf/38/Supplement_1/dead093.900/50786261/dead093.900.pdf |
| Rights: |
https://academic.oup.com/pages/standard-publication-reuse-rights |
| Accession Number: |
edsbas.F6F1CF22 |
| Database: |
BASE |