| Title: |
Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events A 1-Year Follow-up |
| Authors: |
Nguyen, Thanh N.; Qureshi, Muhammad M.; Klein, Piers; Yamagami, Hiroshi; Mikulik, Robert; Czlonkowska, Anna; Abdalkader, Mohamad; Sedova, Petra; Sathya, Anvitha; Lo, Hannah C.; Mansour, Ossama Yassin; Vanguru, Husitha Reddy; Lesaine, Emilie; Tsivgoulis, Georgios; Loochtan, Aaron; Demeestere, Jelle; Uchino, Ken; Inoa, Violiza; Goyal, Nitin; Charidimou, Andreas; Siegler, James E.; Yaghi, Shadi; de Sousa, Diana Aguiar; Mohammaden, Mahmoud H.; Haussen, Diogo C.; Kristoffersen, Espen Saxhaug; Lereis, Virginia Pujol; Scollo, Sergio Daniel; Campbell, Bruce C.; Ma, Alice; Thomas, James Orton; Parsons, Mark W.; Singhal, Shaloo; Slater, Lee-Anne; Martins, Rodrigo Tomazini; Enzinger, Chris; Gattringer, Thomas; Rahman, Aminur; Bonnet, Thomas; Ligot, Noemie; De Raedt, Sylvie; Lemmens, Robin; Vanacker, Peter; Vandervorst, Fenne; Conforto, Adriana Bastos; Hidalgo, Raquel C.T.; Neves, Luciana de Oliveira; Martins, Rodrigo Targa; Mora Cuervo, Daissy Liliana; Rebello, Leticia C.; Santiago, Igor Bessa; da Silva, Isabelle Lameirinhas; Sakelarova, Teodora; Kalpachki, Rosen; Alexiev, Filip; Catanese, Luciana; Cora, Elena Adela; Goyal, Mayank; Hill, Michael D.; Kelly, Michael E.; Khosravani, Houman; Lavoie, Pascale; Peeling, Lissa; Pikula, Aleksandra; Rivera, Rodrigo; Chen, Hui-Sheng; Chen, Yimin; Huo, Xiaochuan; Miao, Zhongrong; Yang, Shuiquan; Bedekovic, Marina Roje; Bralic, Marina; Budincevic, Hrvoje; Corredor-Quintero, Angel Basilio; Lara-Sarabia, Osvaldo E.; Cabal, Martin; Tenora, Dusan; Fibrich, Petr; Herzig, Roman; Hrabanovska, Emanuela; Hlinovsky, David; Jurak, Lubomir; Kadlcikova, Jana; Karpowicz, Igor; Klecka, Lukas; Kovar, Martin; Lauer, David; Neumann, Jiri; Palouskova, Hana; Reiser, Martin; Rekova, Petra; Rohan, Vladimir; Skoda, Ondrej; Skorna, Miroslav; Sramek, Martin; Zakova, Lenka; Christensen, Hanne; Drenck, Nicolas; Iversen, Helle Klingenberg; Truelsen, Thomas Clement; Wienecke, Troels; Sobh, Khalid; Ylikotila, Pauli; Alpay, Kemal; Strbian, Daniel; Bernady, Patricia; Casenave, Philippe; Dan, Maria; Faucheux, Jean-Marc; Gentric, Jean-Christophe; Magro, Elsa; Sabben, Candice; Reiner, Peggy; Rouanet, Francois; Bohmann, Ferdinand O.; Boskamp, Stefan; Mbroh, Joshua; Nagel, Simon; Nolte, Christian H.; Ringleb, Peter A.; Rosenkranz, Michael; Poli, Sven; Thomalla, Gotz; Karapanayiotides, Theodoros; Koutroulou, Ioanna; Kargiotis, Odysseas; Palaiodimou, Lina; Barrientos Guerra, Jose Dominguo; Huded, Vikram; Menon, Bindu; Nagendra, Shashank; Prajapati, Chintan; Sylaja, P.N.; Pramana, Nyoman Angga Krishna; Sani, Achmad Firdaus; Ghoreishi, Abdoreza; Farhoudi, Mehdi; Hokmabadi, Elyar Sadeghi; Abu Raya, Tariq; Kalmanovich, Shani Avnery; Ronen, Levite; Sabetay, Sergiu Ionut; Acampa, Maurizio; Adami, Alessandro; Castellan, Lucio; Longoni, Marco; Ornello, Raffaele; Renieri, Leonardo; Bigliani, Claudia Rolla; Romoli, Michele; Sacco, Simona; Salmaggi, Andrea; Sangalli, Davide; Zini, Andrea; Doijiri, Ryosuke; Fukuda, Hiroki; Fujinaka, Toshiyuki; Fujita, Kyohei; Imamura, Hirotoshi; Sakai, Nobuyuki; Kanamaru, Takuya; Kimura, Naoto; Kono, Ryuhei; Miyake, Kosuke; Sakaguchi, Manabu; Sakai, Kenichiro; Sonoda, Kazutaka; Todo, Kenichi; Miyashita, Fumio; Tokuda, Naoki; Matsumaru, Yuji; Matsumoto, Shoji; Ohara, Nobuyuki; Shindo, Seigo; Takenobu, Yohei; Yoshimoto, Takeshi; Toyoda, Kazunori; Uwatoko, Takeshi; Yagita, Yoshiki; Yamada, Takehiro; Yamamoto, Nobuaki; Yamamoto, Ryoo; Yazawa, Yukako; Sugiura, Yuri; Waweru, Peter Kuria; Baek, Jang-Hyun; Lee, Si Baek; Seo, Kwon-Duk; Sohn, Sung-Il; Arsovska, Anita Ante; Chan, Yong Chieh; Zaidi, Wan Asyraf Wan; Jaafar, Ainul Syahrilfazli; Gongora-Rivera, Fernando; Martinez-Marino, Manuel; Infante-Valenzuela, Adrian; Groppa, Stanislav; Leahu, Pavel; Coutinho, Jonathan M.; Rinkel, Leon A.; Dippel, Diederik W.J.; Van dam-Nolen, Dianne H.K.; Ranta, Annemarei; Wu, Teddy Y.; Adebayo, Tajudeen Temitayo; Bello, Abiodun H.; Nwazor, Ernest Okwundu; Sunmonu, Taofiki Ajao; Wahab, Kolawole Wasiu; Ronning, Ole Morten; Sandset, Else Charlotte; Al Hashmi, Amal M.; Ahmad, Saima; Rashid, Umair; Rodriguez-Kadota, Liliana; Yalung, Patrick Matic; Dy, Jon Stewart Hao; Pineda-Franks, Maria Carissa; Co, Christian Oliver; Brola, Waldemar; Debiec, Aleksander; Dorobek, Malgorzata; Karlinski, Michal Adam; Labuz-Roszak, Beata M.; Lasek-Bal, Anetta; Sienkiewicz-Jarosz, Halina; Staszewski, Jacek; Sobolewski, Piotr; Wiacek, Marcin; Zielinska-Turek, Justyna; Araujo, Andre Pinho; Rocha, Mariana; Castro, Pedro; Cruz, Vitor Tedim; Ferreira, Paulo Venancio; Ferreira, Patricia; Nunes, Ana Paiva; Fonseca, Luisa; Marto, Joao Pedro; Pinho e Melo, Teresa; Rodrigues, Miguel; Silva, M. Luis; Dimitriade, Adela; Falup-Pecurariu, Cristian; Hamid, May Adel; Venketasubramanian, Narayanaswamy; Krastev, Georgi; Mako, Miroslav; Ayo-Martin, Oscar; Hernandez-Ferandez, Francisco; Blasco, Jordi; Rodriguez-Vazquez, Alejandro; Cruz-Culebras, Antonio; Moniche, Francisco; Montaner, Joan; Perez-Sanchez, Soledad; Garcia Sanchez, Maria Jesas; Guillan Rodriguez, Marta; Jood, Katarina; Nordanstig, Annika; Mazya, Michael; Moreira, Tiago T.P.; Bernava, Gianmarco; Beyeler, Morin; Bolognese, Manuel; Carrera, Emmanuel; Dobrocky, Tomas; Karwacki, Grzegorz Marek; Keller, Emanuela; Hsieh, Chang Yang; Boonyakarnkul, Surawan; Churojana, Anchalee; Aykac, Ozlem; Ozdemir, Atilla Azcan; Bajrami, Arsida; Senadim, Songul; Hussain, Syed Irteza; John, Seby; Banerjee, Soma; Kwan, Joseph; Krishnan, Kailash; Lenthall, Robert; Matthews, Ashok; Wong, Ken; Zhang, Liqun; Altschul, Dorothea; Asif, Kaiz S.; Bahiru, Zeelalem; Below, Kristine; Ruland, Sean; Chaudry, Saqib A.; Chen, Michael; Chebl, Alex; Cibulka, Jackie; Cistrunk, Leon; Clark, Judith; Colasurdo, Marco; Czap, Alexandra; de Havenon, Adam; D'Amato, Salvatore; Dharmadhikari, Sushrut; Grimmett, Kasey B.; Dmytriw, Adam A.; Etherton, Mark R.; Ezepue, Chizoba; Farooqui, Mudassir; Feske, Steven K.; Fink, Lauren; Gasimova, Ulviyya; Guzik, Amy K.; Hakemi, Maryam; Hovingh, Majesta; Khan, Muhib; Jillela, Dinesh; Khatri, Rakesh; Khawaja, Ayaz M.; Khoury, Naim N.; Kiley, Nicole L.; Kim, Benny S.; Kolikonda, Murali K.; Kuhn, Anna Luisa; Lara, Stephanie; Linares, Guillermo; Linfante, Italo; Lukovits, Timothy G.; Lycan, Sarah; Male, Shailesh S.; Maali, Laith; Mancin, John; Masoud, Hesham; Mohamed, Ghada A.; Monteiro, Andre; Nahab, Fadi; Nalleballe, Krishna; Ortega-Gutierrez, Santiago; Puri, Ajit S.; Radaideh, Yazan; Rahangdale, Rahul H.; Rai, Ansaar; Ramakrishnan, Pankajavalli; Reddy, Aravind B.; Rojas-Soto, Diana M.; Romero, Jose Rafael; Rost, Natalia S.; Rothstein, Aaron; Omran, Setareh Salehi; Sheth, Sunil A.; Siddiqui, Adnan H.; Starosciak, Amy K.; Tarlov, Nicholas E.; Taylor, Robert A.; Wang, Michael J.; Wolfe, Jared; Wong, Ka-Ho; Huynh, Vu Le; Quy, Viet Nguyen; Thong, Nhu Pham; Trung, Thanh Nguyen; Hoang, Thi Phan; Mai, Duy Ton; Fischer, Urs; Michel, Patrik; Strambo, Davide; Martins, Sheila O.; Zaidat, Osama O.; Nogueira, Raul G. |
| Source: |
ISSN:0028-3878 ; ISSN:1526-632X ; Neurology, vol. 100 (4), (E408-E421. |
| Publisher Information: |
American Academy of Neurology |
| Publication Year: |
2023 |
| Subject Terms: |
Science & Technology; Life Sciences & Biomedicine; Clinical Neurology; Neurosciences & Neurology; Humans; Brain Ischemia; COVID-19; Follow-Up Studies; Intracranial Hemorrhages; Pandemics; Retrospective Studies; SARS-CoV-2; Stroke; Stroke Volume; Thrombectomy; Thrombolytic Therapy; Treatment Outcome; and the SVIN COVID-19 Global Stroke Registry; acute stroke; intracranial hemorrhage; intravenous thrombolysis; ischemic stroke; mechanical thrombectomy; 1103 Clinical Sciences; 1109 Neurosciences; 1702 Cognitive Sciences; Neurology & Neurosurgery; 3202 Clinical sciences; 3209 Neurosciences |
| Description: |
BACKGROUND AND OBJECTIVES: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), IVT, and mechanical thrombectomy over a 1-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020). METHODS: We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, IVT treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases. RESULTS: There were 148,895 stroke admissions in the 1 year immediately before compared with 138,453 admissions during the 1-year pandemic, representing a 7% decline (95% CI [95% CI 7.1-6.9]; p < 0.0001). ICH volumes declined from 29,585 to 28,156 (4.8% [5.1-4.6]; p < 0.0001) and IVT volume from 24,584 to 23,077 (6.1% [6.4-5.8]; p < 0.0001). Larger declines were observed at high-volume compared with low-volume centers (all p < 0.0001). There was no significant change in mechanical thrombectomy volumes (0.7% [0.6-0.9]; p = 0.49). Stroke was diagnosed in 1.3% [1.31-1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82-2.97], 5,656/195,539) of all stroke hospitalizations. DISCUSSION: There was a global decline and shift to lower-volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared with the prior year. Mechanical thrombectomy volumes were preserved. These results suggest ... |
| Document Type: |
article in journal/newspaper |
| File Description: |
application/pdf |
| Language: |
English |
| Relation: |
https://lirias.kuleuven.be/handle/20.500.12942/705890; https://doi.org/10.1212/WNL.0000000000201426; https://pubmed.ncbi.nlm.nih.gov/36257718 |
| DOI: |
10.1212/WNL.0000000000201426 |
| Availability: |
https://lirias.kuleuven.be/handle/20.500.12942/705890; https://hdl.handle.net/20.500.12942/705890; https://lirias.kuleuven.be/retrieve/88df4375-e428-4663-88dd-4d878808e660; https://doi.org/10.1212/WNL.0000000000201426; https://pubmed.ncbi.nlm.nih.gov/36257718 |
| Rights: |
info:eu-repo/semantics/openAccess ; public ; All rights reserved |
| Accession Number: |
edsbas.F76EF0E7 |
| Database: |
BASE |