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Anatomical and functional results of vitrectomy and gas tamponade in macular hole treatment

Title: Anatomical and functional results of vitrectomy and gas tamponade in macular hole treatment
Authors: Novytskyy, Ihor; Tomkiv, U.
Source: Acta Ophthalmologica ; volume 100, issue S275 ; ISSN 1755-375X 1755-3768
Publisher Information: Wiley
Publication Year: 2022
Collection: Wiley Online Library (Open Access Articles via Crossref)
Description: Background: Idiopathic macular holes (IMH) of large sizes are still challenging for vitreoretinal surgeons. Predict factors of the treatment effectiveness are little‐known. Purpose: To evaluate the effectiveness of large idiopathic macular holes surgery with 18% perfluoropropane (C 3 F 8 ) gas tamponade. Methods: The retrospective study, which includes 68 eyes of 68 patients diagnosed with IMH stage 3 or stage 4 (Gass classification) between January 2015 and January 2020. Among them, there were 16 men (23.5%) and 52 women (76.5%). The mean age of patients was 66.7 ± 4.3. Morphologic parameters of the macular hole (base diameter, minimum diameter) were measured and then hole form factor (HFF) was calculated. All eyes underwent 25 gauge pars plana vitrectomy, internal limiting membrane peeling, 18% C 3 F 8 gas tamponade and postoperative face‐down positioning for two weeks. The minimum follow‐up period was 3 months and the mean follow‐up period was 19.6 ± 11.4 months. The main outcome measures were IMH closure confirmed by spectral domain optical coherence tomography at 1 month postoperatively and visual acuity at 3 months postoperatively. Results: No intra‐ and postoperative complications were observed. The IMH were closed in 61 out of 68 eyes at one month after surgery. The anatomic closure rate was 89.7%. The mean base diameter of IMH was 1022.82 ± 292.36 μm (range: 682–2019 μm). The mean minimum diameter of IMH was 471.71 ± 138.73 (range: 258–766 μm). The mean preoperative BCDVA was 0.72 ± 0.29 logMAR and mean postoperative BCDVA at 3 months after surgery was 0.5 ± 0.33 logMAR ( p = 0.063, t‐test). In 47 patients (69.1%) BCDVA improved after surgery. Mean gain in visual acuity at 3 months after operation was 0.20 ± 0.27 (ΔBCDVA, logMAR). Visual acuity worsened or remained unchanged after surgery in 21 patients (30.9%) due to postoperative vitreoretinal interface disorders (foveal thinning, retinal pigment epithelium defects, and foveal cysts). The mean HFF value was 0.77 ± 0.09. There was a ...
Document Type: article in journal/newspaper
Language: English
DOI: 10.1111/j.1755-3768.2022.15396
Availability: https://doi.org/10.1111/j.1755-3768.2022.15396
Rights: http://onlinelibrary.wiley.com/termsAndConditions#vor
Accession Number: edsbas.F7A5FC4F
Database: BASE