Incidence of and socio-biologic risk factors for spontaneous preterm birth in HIV positive Nigerian women
| Title: | Incidence of and socio-biologic risk factors for spontaneous preterm birth in HIV positive Nigerian women |
|---|---|
| Authors: | Ezechi Oliver C; David Agatha N; Gab-Okafor Chidinma V; Ohwodo Harry; Oladele David A; Kalejaiye Olufunto O; Ezeobi Paschal M; Gbajabiamila Titilola A; Adu Rosemary A; Oke Bamidele; Musa Zaidat A; Ekama Sabdat O; Ilesanmi Oluwafunke; Odubela Olutosin; Somefun Esther O; Herbertson Ebiere C; Onwujekwe Dan I; Ujah Innocent AO |
| Source: | BMC Pregnancy and Childbirth, Vol 12, Iss 1, p 93 (2012) |
| Publisher Information: | BMC |
| Publication Year: | 2012 |
| Collection: | Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: | Spontaneous preterm birth/delivery HIV; Pregnancy; Viral load; CD4 count; Low birth weight; Gynecology and obstetrics; RG1-991 |
| Description: | Background Recent studies have identified HIV as a leading contributor to preterm delivery and its associated morbidity and mortality. However little or no information exists in our sub-region on this subject. Identifying the factors associated with preterm delivery in HIV positive women in our country and sub-region will not only prevent mother to child transmission of HIV virus but will also reduce the morbidity and mortality associated with prematurity and low birth weight. This study was designed to determine the incidence and risk factors for preterm delivery in HIV positive Nigerians. Method The required data for this retrospective study was extracted from the data base of a cohort study of the outcome of prevention of mother to child transmission at the Nigerian Institute of Medical Research, Lagos. Only data of women that met the eligibility of spontaneous delivery after 20 weeks of gestation were included. Ethical approval was obtained from the Institution’s Ethical Review Board. Results 181 women out of the 1626 eligible for inclusion into the study had spontaneous preterm delivery (11.1%). The mean birth weight was 3.1 ± 0.4 kg, with 10.3% having LBW. Spontaneous preterm delivery was found to be significantly associated with unmarried status (cOR: 1.7;1.52-2.57), baseline CD4 count |
| Document Type: | article in journal/newspaper |
| Language: | English |
| Relation: | http://www.biomedcentral.com/1471-2393/12/93; https://doaj.org/toc/1471-2393; https://doaj.org/article/4acc30108110455b9c490ec83d023d02 |
| DOI: | 10.1186/1471-2393-12-93 |
| Availability: | https://doi.org/10.1186/1471-2393-12-93; https://doaj.org/article/4acc30108110455b9c490ec83d023d02 |
| Accession Number: | edsbas.F88B8030 |
| Database: | BASE |