| Title: |
SENOSI Confocal Microscopy : A New and Innovating Way to Detect Positive Margins in Non-Palpable Breast Cancer ? |
| Authors: |
Wernly, Deborah; Beniere, Charles; Besse, Valerie; Seidler, Stephanie; Lachat, Regine; Letovanec, Igor; Huber, Daniela; Simonson, Colin |
| Source: |
ISSN: 2075-1729 ; Life, vol. 14, no. 2 (2024) 204. |
| Publication Year: |
2024 |
| Collection: |
Université de Genève: Archive ouverte UNIGE |
| Subject Terms: |
info:eu-repo/classification/ddc/618; Breast cancer; Confocal microscopy; Margins; Surgery |
| Description: |
In Switzerland, breast cancer is the leading cancer among women, with breast-conserving surgery (BCS) being the preferred treatment for small tumors. The margin status post-surgery is a critical predictor of local recurrence. Achieving negative margins remains a challenge, leading to re-excision in 20–30% of cases. Traditional methods like intraoperative examination palpation and radiography have limitations in assessing excised margins. This study introduces the Histolog® Scanner, a confocal microscopy tool, as a potential solution. It provides real-time images of tissue architecture, allowing for rapid and accurate assessment of excised margins. Our research compared the Histolog® Scanner with standard per-operative radiography in patients with non palpable breast cancer. Preliminary results indicate that the Histolog® Scanner offers a reliable and time-efficient method for margin assessment, suggesting its potential for clinical integration. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/38398713; unige:182891 |
| Availability: |
https://archive-ouverte.unige.ch/unige:182891 |
| Rights: |
info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.F88F7CB4 |
| Database: |
BASE |