| Contributors: |
Troisi, Nicola; Michelagnoli, Stefano; Adami, Daniele; Berchiolli, Raffaella; Accrocca, Federico; Amico, Alessio; Angelini, Andrea; Arnuzzo, Luca; Marchetti, Andrea Ascoli; Attisani, Luca; Bafile, Gennaro; Baldino, Giuseppe; Barbanti, Enrico; Bartoli, Stefano; Bellosta, Raffaello; Benedetto, Filippo; Borioni, Raoul; Briolini, Franco; Busoni, Cristina; Camparini, Stefano; Cappiello, Pierluigi; Carbonari, Luciano; Casella, Francesco; Celoria, Giovanni; Chiama, Andrea; Chisci, Emiliano; Civilini, Efrem; Codispoti, Francesco Alberto; Conti, Barbara; Coppi, Giovanni; De Blasis, Giovanni; D'Elia, Marcello; Di Domenico, Rossella; Di Girolamo, Carla; Ercolini, Leonardo; Ferrari, Alessandra; Ferrari, Mauro; Forliti, Enzo; Frigatti, Paolo; Frigerio, Dalmazio; Frosini, Pierfrancesco; Garriboli, Luca; Giordano, Antonio Nicola; Guerrieri, Walter; Jannello, Antonio; Massara, Mafalda; Merlo, Maurizio; Mezzetti, Roberto; Miccoli, Tommaso; Milite, Domenico; Mingazzini, Pietro; Muncinelli, Marina; Nano, Giovanni; Natola, Marco; Novali, Claudio; Palasciano, Giancarlo; Perkmann, Reinhold; Persi, Federica; Petruccelli, David; Pinelli, Mauro; Poletto, Giorgio; Porta, Carla; Pratesi, Carlo; Pruner, Gianguido; Ragazzi, Giovanni; Righini, Paolo; Salvini, Mauro; Scovazzi, Paolo; Setacci, Carlo; Settembrini, Alberto Maria; Siani, Andrea; Silingardi, Roberto; Silvestro, Antonino; Talarico, Francesco; Tolva, Valerio; Trani, Antonio; Trimarchi, Santi; Tshomba, Yamume; Vigliotti, Gennaro; Viola, Daniela; Volpe, Pietro; Zani, Federico |
| Description: |
Background: The aim of this study was to compare the 2-year outcomes of de novo versus postendovascular lesion treatment of femoropopliteal occlusions included in a national, multicenter, observational, prospective registry based on the treatment of critical Limb-threatening IschaeMia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE) registry.Methods: From January 2018 to December 2019, 541 patients from43 centers have been enrolled in the LIMBSAVE registry. Of these patients, 460 were included in the present study: 341 (74.1%) with de novo lesions (DN group) and 119 (25.9%) with postendovascular treatment lesions (PE group). Initial outcome measures were assessed at 30 days after treatment. Furthermore, at the 2-year follow-up, the estimated outcomes of primary patency, primary-assisted patency, secondary patency, and limb salvage were analyzed with Kaplan-Meier curves and compared between groups with the log-rank test.Results: Both groups were homogeneous in terms of demographic data, preoperative risk factors, and clinical presentation. However, compared with DN group, more patients in PE group had a great saphenous vein diameter of less than 3 mm (11.1% vs 21%; P = .007). Intraoperatively, both groups showed similar distal anastomosis sites: below-the-knee popliteal artery (63% DN group, 66.4% PE group) and tibial vessel (37% DN group, 33.6% PE group) (P = .3). The overall mean duration of follow-up was 11.6 months (range, 1-24 months). At the 2-year follow-up, there were no differences between the two groups in terms of primary patency (66.3% DN group vs 74.1% PE group; P = .9), primary-assisted patency (78.2% DN group vs 79.5% PE group; P = .2), secondary patency (85.1% DN group vs 91.4% PE group; P = .2), and limb salvage (95.2% DN group vs 95.1% PE group; P = .9).Conclusions: The LIMBSAVE registry did not show a worsening of overall patency and limb salvages rates at the 2-year follow-up in patients undergoing in situ saphenous bypass after a failed endovascular approach for ... |