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Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes

Title: Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes
Authors: Elyahu, Yehezqel; Hekselman, Idan; Eizenberg-Magar, Inbal; Berner, Omer; Strominger, Itai; Schiller, Maya; Mittal, Kritika; Nemirovsky, Anna; Eremenko, Ekaterina; Vital, Assaf; Simonovsky, Eyal; Chalifa-Caspi, Vered; Friedman, Nir; Yeger-Lotem, Esti; Monsonego, Alon
Contributors: Israel Science Foundation; Litwin and Gural Foundations
Source: Science Advances ; volume 5, issue 8 ; ISSN 2375-2548
Publisher Information: American Association for the Advancement of Science (AAAS)
Publication Year: 2019
Description: Single-cell analysis of CD4 T cells reveals a population structure associated with inflammation and declined immunity in aging.
Document Type: article in journal/newspaper
Language: English
DOI: 10.1126/sciadv.aaw8330
Availability: https://doi.org/10.1126/sciadv.aaw8330; https://www.science.org/doi/pdf/10.1126/sciadv.aaw8330
Accession Number: edsbas.F8D79428
Database: BASE