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LENS - a clinical trial embedded in routine clinical practice to reduce the burden of diabetic eye disease

Title: LENS - a clinical trial embedded in routine clinical practice to reduce the burden of diabetic eye disease
Authors: Preiss, D; Armitage, J; Olson, J; Scotland, G; Leese, G; Colhoun, H; Sattar, N; Murphy, K; Logue, J
Publisher Information: BioMed Central
Publication Year: 2018
Collection: Oxford University Research Archive (ORA)
Description: Embedding clinical trials in routine clinical care provides the opportunity to enhance efficiency and reduce costs. Diabetic retinopathy (DR) remains a common cause of blindness and impaired vision and treatment of advanced DR is costly. However, few trials have been designed to investigate treatments which may retard progression from observable DR to advanced DR because the condition usually progresses slowly, it is challenging to identify patients at risk of progression to clinically significant DR without retinal imaging and studies require medical professionals and specialist equipment to capture and grade retinal images. This highlights the need for streamlined trials which can identify large numbers of eligible patients and follow them cost-effectively for extended periods.
Document Type: conference object
Language: unknown
DOI: 10.1186/s13063-017-1902-y
Availability: https://doi.org/10.1186/s13063-017-1902-y; https://ora.ox.ac.uk/objects/uuid:23b7c1fb-2cc1-4a82-b369-297a355fc57f
Rights: info:eu-repo/semantics/openAccess ; CC Attribution (CC BY)
Accession Number: edsbas.F9DA7556
Database: BASE