| Title: |
From Green Chemistry to Healthy Environments: Silver Nanoparticles as a Dual Antioxidant and Antibacterial Agents for Advancing Biomedicine and Sustainable Wastewater Treatment |
| Authors: |
Moussa, Hamza; Hamid, Sarah; Mameri, Amal; Lekmine, Sabrina; Tahraoui, Hichem; Kebir, Mohammed; Touzout, Nabil; Dahmoune, Farid; Shamsul Ola, Mohammad; Zhang, Jie; Amrane, Abdeltif |
| Contributors: |
Université Mohamed Akli Ouelhadj de Bouira (UMAOB); Université Abderrahmane Mira Université de Béjaïa = University of Béjaïa = جامعة بجاية (UB); Universite Abbes Laghrour Khenchela; Ecole Nationale Supérieure de Chimie de Rennes (ENSCR); Yahya Fares University - Medea = Université Yahia Fares de Médéa Medea, Algeria (YFUM); Institut des Sciences Chimiques de Rennes (ISCR); Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS); Centre de recherche sur l'Information Scientifique et Technique (CERIST); Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.); King Saud University Riyadh (KSU); Newcastle University Newcastle; Researchers Supporting Project Number (RSPD2024R710), King Saud University, Riyadh, Saudi Arabia. |
| Source: |
ISSN: 2306-5354 ; Bioengineering ; https://hal.science/hal-04832953 ; Bioengineering, 2024, 11 (12), pp.1205. ⟨10.3390/bioengineering11121205⟩. |
| Publisher Information: |
CCSD; MDPI |
| Publication Year: |
2024 |
| Subject Terms: |
silver nanoparticles; green synthesis; biological activities; wastewater treatment; [CHIM.GENI]Chemical Sciences/Chemical engineering |
| Description: |
International audience ; The green synthesis of silver nanoparticles (AgNPs) using plant extracts is an eco-friendly method with potential for biomedical and environmental applications. This study aims to synthesize silver nanoparticles (SO-AgNPs) using Salvia officinalis L. extract and evaluate their antioxidant and antibacterial properties, positioning them as candidates for applications in sustainable biomedicine and wastewater treatment. S. officinalis L. extract was used to synthesize AgNPs under optimized conditions, with a 10% extract/AgNO₃ ratio and a reaction time of 180 min. The SO-AgNPs were characterized using ATR-FTIR, XRD, SEM, DLS, and Zeta potential analysis. The antioxidant activity of the extract and SO-AgNPs was evaluated using ABTS+• and DPPH• radical scavenging assays. Antibacterial activity was tested against 11 bacterial strains and bacteria isolated from industrial effluent, with minimal inhibitory concentrations (MIC) determined for both the extract and SO-AgNPs. The SO-AgNPs demonstrated potent antioxidant activity, with IC₅₀ values of 0.233 mg/mL and 0.305 mg/mL in the ABTS+• assay, and 0.173 mg/mL and 0.185 mg/mL in the DPPH• assay for the extract and SO-AgNPs, respectively. Antibacterial testing showed MIC values of 0.25 mg/mL for SO-AgNPs and between 3.12 and 6.25 mg/mL for S. officinalis L. extract against E. coli, P. aeruginosa, A. baumannii, MRSA, B. cereus, and S. epidermidis. For bacteria isolated from industrial effluent, the MIC values were 0.125 mg/mL for SO-AgNPs and 0.5 mg/mL for the extract. This study highlights the dual antioxidant and antibacterial capabilities of S. officinalis L. extract and SO-AgNPs, demonstrating their potential for use in both biomedical and environmental applications, including wastewater treatment. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.3390/bioengineering11121205 |
| Availability: |
https://hal.science/hal-04832953; https://hal.science/hal-04832953v1/document; https://hal.science/hal-04832953v1/file/bioengineering-11-01205-v3.pdf; https://doi.org/10.3390/bioengineering11121205 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.FAA45322 |
| Database: |
BASE |