| Title: |
ThioCORMates: Tunable and Cost‐Effective Carbon Monoxide‐Releasing Molecules |
| Authors: |
DeSimone, Catherine A.; Naqvi, S. Lyla; Tasker, Sarah Z. |
| Contributors: |
American Chemical Society Petroleum Research Fund |
| Source: |
Chemistry – A European Journal ; volume 28, issue 41 ; ISSN 0947-6539 1521-3765 |
| Publisher Information: |
Wiley |
| Publication Year: |
2022 |
| Collection: |
Wiley Online Library (Open Access Articles via Crossref) |
| Description: |
Carbon monoxide‐releasing molecules (CORMs) can offer a safer alternative to CO delivery than the use of CO gas cylinders. Upon treatment with an amine base, S ‐aryl thioformates (“thioCORMates”) release CO nearly quantitatively at room temperature, a gas which can then be harnessed for carbonylative cross‐coupling, biological study, or inorganic synthesis. These bench‐stable molecules are easily synthesized from the corresponding thiophenol and can be electronically tuned to release CO at different rates‐from less than 1 min to greater than 1 h‐offering a practical alternative to existing CORM technology. Finally, isotopically labeled 13 CO can be conveniently generated and used, with the thioCORMate synthesized from 13 C‐formic acid. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1002/chem.202201326 |
| Availability: |
https://doi.org/10.1002/chem.202201326; https://onlinelibrary.wiley.com/doi/pdf/10.1002/chem.202201326; https://onlinelibrary.wiley.com/doi/full-xml/10.1002/chem.202201326 |
| Rights: |
http://onlinelibrary.wiley.com/termsAndConditions#vor |
| Accession Number: |
edsbas.FB5CEE14 |
| Database: |
BASE |