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Chronic kidney disease and outcome of patients with tricuspid regurgitation

Title: Chronic kidney disease and outcome of patients with tricuspid regurgitation
Authors: Loutati, R; Copeland, V; Fefer, P; Barbash, I M; Segev, A; Guetta, V; Mazor, E; Ben-Zekry, S; Hay, I; Klempfner, R; Kuperstein, R; Maor, E
Source: European Heart Journal - Cardiovascular Imaging ; volume 24, issue Supplement_1 ; ISSN 2047-2404 2047-2412
Publisher Information: Oxford University Press (OUP)
Publication Year: 2023
Description: Funding Acknowledgements Type of funding sources: None. Introduction Although chronic kidney disease (CKD) is common among patients with tricuspid regurgitation (TR), these patients are under-represented in clinical trials examining tricuspid transcatheter interventions, and data regarding their outcome are limited. Methods Consecutive echocardiographic reports linked to clinical data from the largest medical center in Israel (2007–2022) were reviewed. Patients were dichotomized into three groups TR groups (mild, moderate and severe), following by stratification according to renal function. The primary outcome was all-cause mortality. Kaplan Meier, Multivariate Cox regression and interaction analysis models were applied. Results The final study population included 78,461 patients with a mean age of 65 (IQR: 55–78 years), 2,998 (4%) of whom had severe TR. There were 11,443 (15%) patients with at least moderate CKD (estimated glomerular filtration rate [eGFR] < 45 mL/min/1.73 m2), 5573 (7%) with eGFR
Document Type: article in journal/newspaper
Language: English
DOI: 10.1093/ehjci/jead119.405
Availability: https://doi.org/10.1093/ehjci/jead119.405; https://academic.oup.com/ehjcimaging/article-pdf/24/Supplement_1/jead119.405/50622443/jead119.405.pdf
Rights: https://academic.oup.com/pages/standard-publication-reuse-rights
Accession Number: edsbas.FBB30AFC
Database: BASE