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Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records

Title: Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records
Authors: Ellen Thompson; DM Williams; AJ Walker; RE Mitchell; CL Niedzwiedz; TC Yang; CF Huggins; ASF Kwong; RJ Silverwood; G Di Gessa; RCE Bowyer; K Northstone; B Hou; MJ Green; B Dodgeon; KJ Doores; EL Duncan; FMK Williams; B MacKenna; P Inglesby; CT Rentsch; HJ Curtis; CE Morton; J Morley; A Mehrkar; S Bacon; G Hickman; C Bates; R Croker; D Evans; T Ward; J Cockburn; S Davy; K Bhaskaran; A Schultze; EJ Williamson; WJ Hulme; HI McDonald; L Tomlinson; R Mathur; RM Eggo; K Wing; AYS Wong; H Forbes; J Tazare; J Parry; F Hester; S Harper; IJ Douglas; SJW Evans; L Smeeth; B Goldacre; A Steptoe; DJ Porteous; RRC McEachan; P Patalay; GB Ploubidis; SV Katikireddi; K Tilling; NJ Timpson; N Chaturvedi; CJ Steves
Publication Year: 2022
Collection: University of Sussex (US): Figshare
Subject Terms: Health sciences; Health services and systems; COVID-19; Electronic Health Records; Female; Humans; Longitudinal Studies; Risk Factors; Surveys and Questionnaires; United Kingdom; Post-Acute COVID-19 Syndrome; OpenSAFELY Collaborative; 4203 Health Services and Systems; 42 Health Sciences; Clinical Research; Coronaviruses Disparities and At-Risk Populations; Coronaviruses; Prevention; Emerging Infectious Diseases; Obesity; Infectious Diseases; Lung; 2.4 Surveillance and distribution; 3 Good Health and Well Being
Description: The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden and possible causes of long COVID in the community, we coordinated analyses of survey data from 6907 individuals with self-reported COVID-19 from 10 UK longitudinal study (LS) samples and 1.1 million individuals with COVID-19 diagnostic codes in electronic healthcare records (EHR) collected by spring 2021. Proportions of presumed COVID-19 cases in LS reporting any symptoms for 12+ weeks ranged from 7.8% and 17% (with 1.2 to 4.8% reporting debilitating symptoms). Increasing age, female sex, white ethnicity, poor pre-pandemic general and mental health, overweight/obesity, and asthma were associated with prolonged symptoms in both LS and EHR data, but findings for other factors, such as cardio-metabolic parameters, were inconclusive.
Document Type: article in journal/newspaper
Language: unknown
Relation: 10779/uos.29211716.v1; https://figshare.com/articles/journal_contribution/Long_COVID_burden_and_risk_factors_in_10_UK_longitudinal_studies_and_electronic_health_records/29211716
Availability: https://figshare.com/articles/journal_contribution/Long_COVID_burden_and_risk_factors_in_10_UK_longitudinal_studies_and_electronic_health_records/29211716
Rights: CC BY 4.0
Accession Number: edsbas.FBD67260
Database: BASE