| Title: |
Lower respiratory infections among hospitalized children in New Caledonia: a pilot study for the Pneumonia Etiology Research for Child Health project. |
| Authors: |
Mermond, Sylvain; Zurawski, Virginie; d'Ortenzio, Eric; Driscoll, Amanda J; Deluca, Andrea N; Deloria-Knoll, Maria; Moïsi, Jennifer C; Murdoch, David R; Missotte, Isabelle; Besson-Leaud, Laurent; Chevalier, Cyril; Debarnot, Vincent; Feray, Fabien; Noireterre, Stephanie; Duparc, Bernard; Fresnais, Frederique; O'Connor, Olivia; Dupont-Rouzeyrol, Myrielle; Levine, Orin S |
| Contributors: |
Institut Pasteur de Nouvelle-Calédonie; Pasteur Network (Réseau International des Instituts Pasteur); International Vaccine Access Center, Department of International Health; Johns Hopkins Bloomberg School of Public Health Baltimore; Johns Hopkins University (JHU)-Johns Hopkins University (JHU); Agence de Médecine Préventive; Department of Pathology; University of Otago Dunedin, Nouvelle-Zélande; Microbiology Unit; Canterbury Health Laboratories; Department of Paediatrics; New Caledonia Hospital; Department of Physical Medicine and Rehabilitation; Department of Radiology |
| Source: |
ISSN: 1058-4838. |
| Publisher Information: |
CCSD; Oxford University Press (OUP) |
| Publication Year: |
2012 |
| Collection: |
Réseau International des Instituts Pasteur, Paris: HAL-RIIP |
| Subject Terms: |
MESH: Adolescent; MESH: Antigens; Viral; MESH: Infant; MESH: New Caledonia; MESH: Picornaviridae Infections; MESH: Pilot Projects; MESH: Pneumonia; MESH: Prospective Studies; MESH: Respiratory Syncytial Virus Infections; MESH: Respiratory Syncytial Viruses; MESH: Respiratory Tract Infections; MESH: Rhinovirus; MESH: Bacteria; MESH: Serologic Tests; MESH: Specimen Handling; MESH: Sputum; MESH: Bacterial Infections; MESH: Case-Control Studies; MESH: Child; Hospitalized; Preschool; MESH: Fluorescent Antibody Technique; MESH: Humans; [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases |
| Description: |
International audience ; We conducted a prospective pilot study over a 1-year period in New Caledonia in preparation for the Pneumonia Research for Child Health (PERCH) project. The pathogens associated with hospitalized lower respiratory infections in children were identified through the use of culture of induced sputum and blood, urinary antigen detection, polymerase chain reaction (PCR) on respiratory specimens, and serology on paired sera. Respiratory viruses were detected on respiratory specimens by immunofluorescence and PCR, and by serology on paired sera. Pathogens were detected in 87.9% of the 108 hospitalized cases. Viruses represented 81.6% of the 152 pathogens detected. Respiratory syncytial virus and rhinovirus were the most frequent, accounting for 32.2% and 24.3% of the pathogens identified, respectively. Only 26.3% of 99 induced sputum specimens collected were determined to be of good quality, which may be a consequence of the collection method used. |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
info:eu-repo/semantics/altIdentifier/pmid/22403234; PUBMED: 22403234 |
| DOI: |
10.1093/cid/cir1070 |
| Availability: |
https://riip.hal.science/pasteur-00769465; https://riip.hal.science/pasteur-00769465v1/document; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Table_1-_20110906.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_20110906.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Figure_1_-_20110827.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Figure_2_-_20110827.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Table_2_-20110905.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Table_3_-_20110905.pdf; https://riip.hal.science/pasteur-00769465v1/file/PERCH-NC_-_Table_4_-_20110827.pdf; https://doi.org/10.1093/cid/cir1070 |
| Rights: |
info:eu-repo/semantics/OpenAccess |
| Accession Number: |
edsbas.FC150A64 |
| Database: |
BASE |