| Title: |
Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes |
| Authors: |
Heras, Marta; Alonso Espias, Maria; Arencibia, Octavio; Minig, Lucas; Martí, Lola; Diestro, Maria Dolores; Cespedes, Juan; Níguez, Isabel; Gil Ibáñez, Blanca; Díaz Feijoo, Berta; Llueca, Antoni; Rosado, Claudia; Iacoponi, Sara; Lopez de la Manzanara, Carlos; Morales, Sara; Fernández Galguera, María José; Cano, Ana; Gorostidi, Mikel; Zapardiel, Ignacio |
| Source: |
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
| Publisher Information: |
MDPI AG |
| Publication Year: |
2024 |
| Collection: |
Dipòsit Digital de la Universitat de Barcelona |
| Subject Terms: |
Càncer d'ovari; Fecunditat; Ovarian cancer; Fertility |
| Description: |
Background: to prove the effectivity of fertility-sparing procedures in early-stage ovarian cancer by assessing pregnancy rates and obstetrical outcomes. Methods: we performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients from 18 to 40 years old with diagnosis of early-stage ovarian cancer, epithelial (EOC) or non-epithelial (non-EOC), from January 2010 to December 2019. Data on the use of assisted reproductive techniques, pregnancy attempts and obstetrical outcomes were collected. Results: a total of 150 patients met inclusion criteria, 70 (46.6%) EOC and 80 (53.4%) non-EOC. Pregnancy attempts were reported in 51 (34%) patients, with 42 (28%) patients carrying the pregnancy to term. Among them, 30 (71.4%) underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. A total of 32 (76.1% patients) had spontaneous pregnancies and 10 (23.9%) required in vitro fertilization. There was only one (2.4%) complication reported. Vaginal delivery was reported in twenty-nine (69%) patients and cesarean section in five (11.9%) patients. Conclusions: fertility-sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complications. The selection of patients must consider strict criteria in order to maintain a good prognosis. |
| Document Type: |
article in journal/newspaper |
| File Description: |
10 p.; application/pdf |
| Language: |
English |
| Relation: |
Reproducció del document publicat a: https://doi.org/10.3390/diagnostics14131424; Diagnostics, 2024, vol. 14, num. 13; https://doi.org/10.3390/diagnostics14131424; https://hdl.handle.net/2445/214871 |
| Availability: |
https://hdl.handle.net/2445/214871 |
| Rights: |
cc by (c) Heras, Marta et al, 2024 ; http://creativecommons.org/licenses/by/3.0/es/ ; info:eu-repo/semantics/openAccess |
| Accession Number: |
edsbas.FC90EF67 |
| Database: |
BASE |