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Clinical Data of Neonatal Systemic Thrombosis

Title: Clinical Data of Neonatal Systemic Thrombosis
Authors: Saracco P.; Bagna R.; Gentilomo C.; Magarotto M.; Viano A.; Magnetti F.; Giordano P.; Luciani M.; Molinari A. C.; Suppiej A.; Ramenghi L. A.; Simioni P.
Contributors: Saracco, P.; Bagna, R.; Gentilomo, C.; Magarotto, M.; Viano, A.; Magnetti, F.; Giordano, P.; Luciani, M.; Molinari, A. C.; Suppiej, A.; Ramenghi, L. A.; Simioni, P.
Publisher Information: Mosby Inc.; NEW YORK
Publication Year: 2016
Collection: Università degli Studi di Genova: CINECA IRIS
Subject Terms: Anticoagulant; Arterie; Coronary Circulation; Data Collection; Female; Gestational Age; Human; Infant; Newborn; Italy; Male; Models; Statistical; Neonatology; Patient Discharge; Registrie; Risk Factor; Sepsi; Thrombophilia; Venous Thromboembolism
Description: Objective To evaluate clinical data and associated risk conditions of noncerebral systemic venous thromboembolism (VT), arterial thromboembolism (AT), and intracardiac thromboembolism (ICT) in neonates. Study design Data analysis of first systemic thromboembolism occurring in 75 live neonates (0-28 days), enrolled in the Italian Registry of Pediatric Thrombosis from neonatology centers between January 2007 and July 2013. Results Among 75 events, 41 (55%) were VT, 22 (29%) AT, and 12 (16%) ICT; males represented 65%, and 71% were preterm. In 19 (25%), thromboembolism was diagnosed on the first day of life. In this "early onset" group, prenatal-associated risk conditions (maternal/placental disease) were reported in 70% and inherited thrombophilia in 33%. Postnatal risk factors were present in 73%; infections and central vascular catheters in 56% and 54% VT, respectively, and in 67% ICT vs 27% AT (
Document Type: article in journal/newspaper
File Description: STAMPA
Language: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/26787378; info:eu-repo/semantics/altIdentifier/wos/WOS:000372753600017; volume:171; firstpage:60; lastpage:66.e1; numberofpages:8; journal:THE JOURNAL OF PEDIATRICS; https://hdl.handle.net/11567/1027406
DOI: 10.1016/j.jpeds.2015.12.035
Availability: https://hdl.handle.net/11567/1027406; https://doi.org/10.1016/j.jpeds.2015.12.035
Rights: info:eu-repo/semantics/closedAccess
Accession Number: edsbas.FD151EB1
Database: BASE