| Title: |
Assessment of the Likelihood of Insulin Resistance and Type 2 Diabetes Mellitus Based on Serum Resistin Status among Nigerians |
| Authors: |
Johnbosco Chidozie Okafor; Ehimen P. Odum; Henry C. Okpara; Collins Amadi |
| Source: |
Nigerian Postgraduate Medical Journal, Vol 33, Iss 2, Pp 192-198 (2026) |
| Publisher Information: |
Wolters Kluwer Medknow Publications |
| Publication Year: |
2026 |
| Collection: |
Directory of Open Access Journals: DOAJ Articles |
| Subject Terms: |
insulin resistance; resistin; type 2 diabetes mellitus; Medicine |
| Description: |
Background: Raised serum resistin is adjudged to increase the likelihood of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) through multiple biochemical pathways. Aims: The current study assessed the likelihood of IR and T2DM among Nigerians based on serum resistin status. Materials and Methods: This case-controlled study was conducted at a tertiary hospital in southern Nigeria, among 100 T2DM patients matched with age/gender controls. Sociodemographic, anthropometric, clinical, and laboratory data, including serum resistin status, were collected using standard protocols. T2DM diagnosis was made using recommended guidelines. Statistical analyses were conducted using descriptive statistics, logistic regression models, and area under the curve (AUC) of the receiver-operating characteristic curve at a 95% confidence level (CI) and an alpha value of |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| Relation: |
https://journals.lww.com/10.4103/npmj.npmj_458_25; https://doaj.org/toc/1117-1936; https://doaj.org/toc/2468-6875; https://doaj.org/article/0e5aa7fbce634d1ca51468a3c6fed968 |
| DOI: |
10.4103/npmj.npmj_458_25 |
| Availability: |
https://doi.org/10.4103/npmj.npmj_458_25; https://doaj.org/article/0e5aa7fbce634d1ca51468a3c6fed968 |
| Accession Number: |
edsbas.FE0049 |
| Database: |
BASE |