| Title: |
Invasive Hemodynamics and Risk Stratification in T-TEER: Moving Beyond ESC Thresholds - EuroTR Registry Insights |
| Authors: |
Masiero, Giulia; Arturi, Federico; Ceni, Sara; Panza, Andrea; Kresoja, Karl-Patrik; von Stein, Jennifer; Fortmeier, Vera; Koell, Benedikt; Rottbauer, Wolfgang; Kassar, Mohammad; Goebel, Bjoern; Denti, Paolo; Achouh, Paul; Rassaf, Tienush; Barreiro-Perez, Manuel; Boekstegers, Peter; Rück, Andreas; Zdanyte, Monika; Adamo, Marianna; Vincent, Flavien; Schlegel, Philipp; Rosch, Sebastian; Wild, Mirjam G.; Besler, Christian; Toggweiler, Stefan; Brunner, Stephanie; Grapsa, Julia; Patterson, Tiffany; Thiele, Holger; Kister, Tobias; Sticchi, Alessandro; De Carlo, Marco; Voss, Fabian; Polzin, Amin; Popolo Rubbio, Antonio; Bedogni, Francesco; Stolte, Thorald; Nestelberger, Thomas; Benito-González, Tomás; Sánchez-Muñóz, Enrique; Konstandin, Mathias H.; Van Belle, Eric; Metra, Marco; Geisler, Tobias; Estévez-Loureiro, Rodrigo; Mahabadi, Amir Abbas; Karam, Nicole; Maisano, Francesco; Lauten, Philipp; Praz, Fabien |
| Source: |
Circulation: Cardiovascular Interventions ; volume 19, issue 1 ; ISSN 1941-7640 1941-7632 |
| Publisher Information: |
Ovid Technologies (Wolters Kluwer Health) |
| Publication Year: |
2026 |
| Description: |
BACKGROUND: Right heart catheterization plays a pivotal role in the preprocedural evaluation of patients considered for transcatheter tricuspid valve edge-to-edge repair. This study aimed to explore the potential impact of hemodynamic parameters obtained through right heart catheterization on patient-centered outcomes. METHODS: This study represents a subanalysis from the multicenter EuroTR registry (European Registry of Transcatheter Repair for Tricuspid Regurgitation). Patients with invasive hemodynamic data who underwent isolated transcatheter tricuspid valve edge-to-edge repair for significant tricuspid regurgitation were included. Outcomes of interest were a composite of 2-year all-cause death or hospitalization for heart failure (HFH) and a patient-centered composite of 6-month all-cause mortality, HFH, New York Heart Association class IV/worsening New York Heart Association class compared with baseline. Secondary outcome included postprocedural New York Heart Association class improvement. RESULTS: Seven hundred and eleven patients were included in the analysis. Two-year survival free from death and HFH was 63%. Optimal prognostic thresholds identified for death and HFH at 2 years were: mean pulmonary artery pressure≥32 mm Hg, pulmonary capillary wedge pressure (PCWP)≥20 mm Hg, and pulmonary vascular resistance≥5 wood units (WU). The early patient-centered composite outcome occurred in 25% of cases. PCWP≥20 mm Hg was independently associated with an early clinical deterioration (hazard ratio, 2.77 [95% CI, 1.47–5.28]; P |
| Document Type: |
article in journal/newspaper |
| Language: |
English |
| DOI: |
10.1161/circinterventions.125.015964 |
| DOI: |
10.1161/CIRCINTERVENTIONS.125.015964 |
| Availability: |
https://doi.org/10.1161/circinterventions.125.015964; https://www.ahajournals.org/doi/full/10.1161/CIRCINTERVENTIONS.125.015964 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| Accession Number: |
edsbas.FE6127DB |
| Database: |
BASE |