| Title: |
Anxiety and depression symptoms after COVID-19 infection: results from the COVID Symptom Study app |
| Authors: |
K Klaser; Ellen Thompson; LH Nguyen; CH Sudre; M Antonelli; B Murray; LS Canas; E Molteni; MS Graham; E Kerfoot; L Chen; J Deng; A May; C Hu; A Guest; S Selvachandran; DA Drew; M Modat; AT Chan; J Wolf; TD Spector; A Hammers; EL Duncan; S Ourselin; CJ Steves |
| Publication Year: |
2021 |
| Collection: |
University of Sussex (US): Figshare |
| Subject Terms: |
Biomedical and clinical sciences; Clinical sciences; Neurosciences; Psychology; COVID-19; depression; psychiatry; Adolescent; Adult; Aged; 80 and over; Anxiety; Female; Humans; Male; Mental Health; Middle Aged; Mobile Applications; Prevalence; SARS-CoV-2; Self Report; Young Adult; 32 Biomedical and Clinical Sciences; 3202 Clinical Sciences; Brain Disorders; Obesity; Mental Illness; Coronaviruses; Infectious Diseases; Behavioral and Social Science |
| Description: |
Background: Mental health issues have been reported after SARS-CoV-2 infection. However, comparison to prevalence in uninfected individuals and contribution from common risk factors (eg, obesity and comorbidities) have not been examined. We identified how COVID-19 relates to mental health in the large community-based COVID Symptom Study. Methods: We assessed anxiety and depression symptoms using two validated questionnaires in 413148 individuals between February and April 2021; 26998 had tested positive for SARS-CoV-2. We adjusted for physical and mental prepandemic comorbidities, body mass index (BMI), age and sex. Findings Overall, 26.4% of participants met screening criteria for general anxiety and depression. Anxiety and depression were slightly more prevalent in previously SARS-CoV-2-positive (30.4%) vs SARS-CoV-2-negative (26.1%) individuals. This association was small compared with the effect of an unhealthy BMI and the presence of other comorbidities, and not evident in younger participants (≤40 years). Findings were robust to multiple sensitivity analyses. Association between SARS-CoV-2 infection and anxiety and depression was stronger in individuals with recent (120 days) infection, suggesting a short-term effect. Interpretation A small association was identified between SARS-CoV-2 infection and anxiety and depression symptoms. The proportion meeting criteria for self-reported anxiety and depression disorders is only slightly higher than prepandemic. |
| Document Type: |
article in journal/newspaper |
| Language: |
unknown |
| Relation: |
10779/uos.29211512.v1 |
| Availability: |
https://figshare.com/articles/journal_contribution/Anxiety_and_depression_symptoms_after_COVID-19_infection_results_from_the_COVID_Symptom_Study_app/29211512 |
| Rights: |
CC BY 4.0 |
| Accession Number: |
edsbas.FF3F6217 |
| Database: |
BASE |