| Title: |
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative. |
| Authors: |
Prowle, JR; Forni, LG; Bell, M; Chew, MS; Edwards, M; Grams, ME; Grocott, MPW; Liu, KD; McIlroy, D; Murray, PT; Ostermann, M; Zarbock, A; Bagshaw, SM; Bartz, R; Bell, S; Bihorac, A; Gan, TJ; Hobson, CE; Joannidis, M; Koyner, JL; Levett, DZH; Mehta, RL; Miller, TE; Mythen, MG; Nadim, MK; Pearse, RM; Rimmele, T; Ronco, C; Shaw, AD; Kellum, JA |
| Source: |
Nature Reviews Nephrology (2021) (In press). |
| Publication Year: |
2021 |
| Collection: |
University College London: UCL Discovery |
| Subject Terms: |
Acute kidney injury: Kidney; Surgery |
| Description: |
Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes, including increased risk of chronic kidney disease, cardiovascular events and death. Risk factors for PO-AKI include older age and comorbid diseases such as chronic kidney disease and diabetes mellitus. PO-AKI is best defined as AKI occurring within 7 days of an operative intervention using the Kidney Disease Improving Global Outcomes (KDIGO) definition of AKI; however, additional prognostic information may be gained from detailed clinical assessment and other diagnostic investigations in the form of a focused kidney health assessment (KHA). Prevention of PO-AKI is largely based on identification of high baseline risk, monitoring and reduction of nephrotoxic insults, whereas treatment involves the application of a bundle of interventions to avoid secondary kidney injury and mitigate the severity of AKI. As PO-AKI is strongly associated with long-term adverse outcomes, some form of follow-up KHA is essential; however, the form and location of this will be dictated by the nature and severity of the AKI. In this Consensus Statement, we provide graded recommendations for AKI after non-cardiac surgery and highlight priorities for future research. |
| Document Type: |
article in journal/newspaper |
| File Description: |
text |
| Language: |
English |
| Relation: |
https://discovery.ucl.ac.uk/id/eprint/10128677/ |
| Availability: |
https://discovery.ucl.ac.uk/id/eprint/10128677/1/s41581-021-00418-2.pdf; https://discovery.ucl.ac.uk/id/eprint/10128677/ |
| Rights: |
open |
| Accession Number: |
edsbas.FF5D6057 |
| Database: |
BASE |