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Warfarin Related Kidney Damage: A Confusing Case of Thrombophlebitis Masquerading as Infection

Title: Warfarin Related Kidney Damage: A Confusing Case of Thrombophlebitis Masquerading as Infection
Authors: Samuelson Brittanee; Decker Matthew; Scott Hannah; Garrison Gregory
Source: Journal of Primary Care & Community Health, Vol 14 (2023)
Publisher Information: SAGE Publishing, 2023.
Publication Year: 2023
Collection: LCC:Computer applications to medicine. Medical informatics; LCC:Public aspects of medicine
Subject Terms: Computer applications to medicine. Medical informatics; R858-859.7; Public aspects of medicine; RA1-1270
Description: Anticoagulant-related nephropathy (ARN) is a rare, newly recognized cause of acute kidney injury and significant but underdiagnosed complication of anticoagulation therapy. ARN occurs in patients taking oral anticoagulant therapy most often warfarin or a novel oral anticoagulant (NOAC). It is a potentially devastating disorder with serious renal consequences and increased all-cause mortality. Anticoagulant-related nephropathy presents as an acute kidney injury (AKI) in the setting of a supratherapeutic INR with profuse glomerular hemorrhage seen as renal tubules filled with red cells and red cell casts on renal biopsy. Being that millions of Americans are on warfarin, a thorough understanding and awareness of the clinical presentation, diagnosis, and therapeutic interventions are crucial to protecting the renal function, lowering all-cause mortality and optimizing treatment. Our goal is to provide education on a newly recognized form of AKI and significant but underdiagnosed complication of anticoagulation therapy.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2150-1327
Relation: https://doaj.org/toc/2150-1327
DOI: 10.1177/21501319231159978
Access URL: https://doaj.org/article/05bafb3a72a541ef87fa9d5fa22b8dcf
Accession Number: edsdoj.05bafb3a72a541ef87fa9d5fa22b8dcf
Database: Directory of Open Access Journals