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Machine Learning based Model Reveals the Metabolites Involved in Coronary Artery Disease

Title: Machine Learning based Model Reveals the Metabolites Involved in Coronary Artery Disease
Authors: Fathima Lamya; Muhammad Arif; Mahbuba Rahman; Abdul Rehman Zar Gul; Tanvir Alam
Source: Biomedical Engineering and Computational Biology, Vol 16 (2025)
Publisher Information: SAGE Publishing, 2025.
Publication Year: 2025
Collection: LCC:Biology (General)
Subject Terms: Biology (General); QH301-705.5
Description: Introduction: Coronary artery disease (CAD) is a major global cause of morbidity and mortality. Therefore, advances in early identification and individualized treatment plans are crucial. Methods: This article presents machine learning (ML) based model that can recognize metabolomic compounds associated with CAD in the Qatari population for the early detection of CAD. We also identified statistically significant metabolic profiles and potential biomarkers using ML methods. Results: Among all ML models, artificial neural network (ANN) outstands all with an accuracy of 91.67%, recall of 80.0%, and specificity of 100%. The results show that 173 metabolites ( P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1179-5972
Relation: https://doaj.org/toc/1179-5972
DOI: 10.1177/11795972251352014
Access URL: https://doaj.org/article/cce08c0d3083417ea54e00aeb56715c1
Accession Number: edsdoj.08c0d3083417ea54e00aeb56715c1
Database: Directory of Open Access Journals