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Opioid Overdose With Parkinsonian Features

Title: Opioid Overdose With Parkinsonian Features
Authors: Paul Cohen; Jason B. Hack
Source: Clinical Practice and Cases in Emergency Medicine, Vol 3, Iss 4 (2019)
Publisher Information: eScholarship Publishing, University of California, 2019.
Publication Year: 2019
Collection: LCC:Medical emergencies. Critical care. Intensive care. First aid
Subject Terms: Medical emergencies. Critical care. Intensive care. First aid; RC86-88.9
Description: A 54-year-old man presented to the emergency department with confusion and Parkinsonian features after suspected heroin snorting. He had magnetic resonance imaging of the brain demonstrating isolated symmetric bilateral globus pallidus (GP) restricted diffusion and edema consistent with hypoxic ischemic encephalopathy. In contrast to other anoxic/ischemic insults, where the GP is preferentially spared, autopsy reports on intravenous heroin users have found the GP to be specifically affected, often demonstrating symmetric bilateral lesions. Opioid toxicity should be considered in patients presenting with Parkinsonian features on examination or pallidal lesions on imaging, especially in younger adults where infarction is less common.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2474-252X
Relation: https://escholarship.org/uc/item/4v04g7t4; https://doaj.org/toc/2474-252X
DOI: 10.5811/cpcem.2019.7.43537
Access URL: https://doaj.org/article/de30765aa73a4ea7941fdaaf739d2d2a
Accession Number: edsdoj.30765aa73a4ea7941fdaaf739d2d2a
Database: Directory of Open Access Journals