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Surgery for adrenal gland disease. Experience of a tertiary center

Title: Surgery for adrenal gland disease. Experience of a tertiary center
Authors: Gaia Cicioni; Immacolata Iannone; Daniele Crocetti; Mariarita Tarallo; Paolo Sapienza; Giuseppe Cavallaro; Giorgio De Toma; Luigi Petramala; Claudio Letizia; Maria Irene Bellini
Source: Surgery Open Science, Vol 30, Iss , Pp 46-50 (2026)
Publisher Information: Elsevier, 2026.
Publication Year: 2026
Collection: LCC:Surgery
Subject Terms: Surgery; RD1-811
Description: Introduction: Laparoscopic adrenalectomy and robotic adrenalectomy are increasingly accepted methods for removing adrenal lesions, especially for benign conditions. This study investigated the evolution of surgical techniques and patient characteristics at a tertiary centre during the transition from open to minimally invasive surgery. Patients and methods: The analysis included all adrenal surgery cases referred to our institution between January 2009 and June 2025. The following were recorded for each patient: demographics, diagnosis, surgical approach, intraoperative blood loss, histology, length of hospital stays, and complications. Results: A total of 292 adrenalectomies were performed (56% female; mean age 54.5 ± 12.6 years). The left adrenal was more frequently affected (59%), and the mean tumor size was 46.8 ± 25.1 mm. Indications included primary hyperaldosteronism (37%), Cushing's syndrome (28%), pheochromocytoma (15%), adrenal cysts or myelolipomas (17%), adrenocortical carcinomas (4%), and adrenal metastases (2%). Laparoscopy was the most common approach (76%), followed by open (10%) and robotic adrenalectomy (9%); overall 7 (2%) patients required conversion to open surgery and postoperative morbidity was 7%. Minimally invasive procedures were associated with shorter operative times, less blood loss, and shorter in-hospital stays when compared to open surgery (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2589-8450
Relation: http://www.sciencedirect.com/science/article/pii/S2589845026000102; https://doaj.org/toc/2589-8450
DOI: 10.1016/j.sopen.2026.01.009
Access URL: https://doaj.org/article/4e448204e54f4e9fa0848708b4212cbc
Accession Number: edsdoj.4e448204e54f4e9fa0848708b4212cbc
Database: Directory of Open Access Journals