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Advancements in curcuminoid formulations: An update on bioavailability enhancement strategies curcuminoid bioavailability and formulations

Title: Advancements in curcuminoid formulations: An update on bioavailability enhancement strategies curcuminoid bioavailability and formulations
Authors: Darmonkow Alexander; Rowe Zoë E. M.; Harding Scott V.
Source: Open Life Sciences, Vol 20, Iss 1, Pp 2930-33 (2025)
Publisher Information: De Gruyter, 2025.
Publication Year: 2025
Collection: LCC:Biology (General)
Subject Terms: curcumin; bioavailability; dietary supplement; functional food; Biology (General); QH301-705.5
Description: Here, we provide a current review of strategies aimed at improving the bioavailability of curcuminoids, a group of compounds with therapeutic potential. This review discusses formulations from the traditional supplementation approaches to the innovative methods to enhance solubility and bioavailability, including cyclodextrins and hydrophilic carriers. Additionally, colloidal delivery strategies, such as micelles, liposomes, solid lipid particles, and emulsions, are examined as promising vehicles for curcuminoid delivery. The review underscores the importance of clinical trials in assessing the efficacy of these formulations and highlights a pivotal yet frequently neglected factor in curcuminoid research: the differentiation between total and free curcuminoid quantification. In summary, this concise review evaluates existing curcuminoid formulations and explores innovative approaches to improve their bioavailability.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2391-5412
Relation: https://doaj.org/toc/2391-5412
DOI: 10.1515/biol-2025-1112
Access URL: https://doaj.org/article/e71c4dc90ff44acdbbbddeef6cc44ec5
Accession Number: edsdoj.71c4dc90ff44acdbbbddeef6cc44ec5
Database: Directory of Open Access Journals